HitPredict

Interactor 1: PWP1 (Q13610)
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)
Gene: PWP1

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	33355139
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Hs			1 1507
+	Hs
		792949 LIS1_HUMAN (25-461): 1.23e-81: 261: 12.94		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		903418 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		792967 LIS1_HUMAN (25-461): 1.23e-81: 261: 12.94		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		1281292 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Hs
		793026 LIS1_HUMAN (25-461): 1.23e-81: 261: 12.94		KTNB1_HUMAN (1066-1211): 2.14e-23: 109: 14.77
+	Hs
		903349 WDR5B_HUMAN (28-370): 4.44e-55: 189: 12.68		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		792935 LIS1_HUMAN (25-461): 1.23e-81: 261: 12.94		LIS1_HUMAN (1255-1393): 1.71e-14: 79.5: 10.14
+	Mm
		925836 LIS1_MOUSE (25-461): 8.62e-82: 261: 12.94		LIS1_MOUSE (1255-1393): 1.71e-14: 79.5: 10.14
+	Hs
		929603 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		903428 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Sc
		744605 TAF5_YEAST (38-477): 1.32e-71: 244: 17.13		TAF5_YEAST (1096-1284): 5.18e-13: 76: 16.10
+	Hs
		1281473 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		PRP19_HUMAN (1068-1205): 4.06e-13: 76: 14.09
+	Hs
		903204 PWP1_HUMAN (299-500): 6.9e-30: 124: 13.91		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		197071 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		PRP4_HUMAN (1178-1389): 5.63e-30: 128: 11.74
+	Hs
		929610 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		921751 GBB2_HUMAN (247-492): 1.81e-36: 139: 15.75		NLE1_HUMAN (972-1164): 2.95e-28: 122: 14.43
+	Hs
		920934 GBB1_HUMAN (247-492): 2.59e-37: 141: 15.75		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Mm
		921089 GBB1_MOUSE (247-492): 2.59e-37: 141: 15.75		RACK1_MOUSE (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		921518 GBB2_HUMAN (247-492): 1.81e-36: 139: 15.75		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		1288388 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		PRP19_HUMAN (1068-1205): 4.06e-13: 76: 14.09