HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: DDX56 (Q9NY93)
Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56)
Gene: DDX56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 776 Hs			1 547
+	Hs
		1041127 CUL1_HUMAN (1-776): 0: 911: 100.00		DDX17_HUMAN (4-467): 9.05e-132: 402: 23.44
+	Hs
		571441 CUL1_HUMAN (1-776): 0: 911: 100.00		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		134026 CUL1_HUMAN (1-776): 0: 911: 100.00		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		1043261 CUL4A_HUMAN (7-776): 0: 781: 30.41		DDX56_HUMAN (1-547): 3.44e-158: 464: 100.00
+	Hs
		1043618 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX56_HUMAN (1-547): 3.44e-158: 464: 100.00
+	Hs
		1042680 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX56_HUMAN (1-547): 3.44e-158: 464: 100.00
+	Hs
		1043492 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX17_HUMAN (4-467): 9.05e-132: 402: 23.44
+	Hs
		571444 CUL4A_HUMAN (7-776): 0: 781: 30.41		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		571445 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		1042199 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX17_HUMAN (4-467): 9.05e-132: 402: 23.44
+	Hs
		134029 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		571443 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Mm
		1207268 CUL3_MOUSE (9-776): 0: 747: 30.35		Q8BTS0_MOUSE (4-418): 1.72e-129: 393: 24.52
+	Hs
		1041422 CUL2_HUMAN (13-776): 0: 720: 35.98		DDX17_HUMAN (4-467): 9.05e-132: 402: 23.44
+	Hs
		134028 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		571442 CUL2_HUMAN (13-776): 0: 720: 35.98		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		134027 CUL2_HUMAN (13-776): 0: 720: 35.98		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		757602 CUL1_HUMAN (1-776): 0: 911: 100.00		IF4A3_HUMAN (9-403): 3.82e-44: 163: 28.12
+	Hs
		640470 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX6_HUMAN (9-407): 9.42e-46: 169: 29.78
+	Hs
		757603 CUL3_HUMAN (9-776): 0: 748: 30.47		IF4A3_HUMAN (9-403): 3.82e-44: 163: 28.12