HitPredict

Interactor 1: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 236
+	Hs
		1041139 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		988301 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Mm
		890920 CAV1_MOUSE (1-178): 4.65e-108: 308: 94.94		RAC1_MOUSE (32-217): 7.38e-78: 234: 53.23
+	Hs
		601249 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RHOQ_HUMAN (23-236): 1.98e-75: 228: 50.00
+	Hs
		953403 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		581003 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		961974 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		1015381 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		955079 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		1041288 CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00		RHOJ_HUMAN (32-214): 8.34e-59: 186: 50.27
+	Hs
		905738 CAV2_HUMAN (53-177): 5.12e-59: 183: 40.80		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17