HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: ARI1 (Q9Y4X5)
E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1)
Gene: ARIH1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 21145461, 28514442, 27565346, 33961781, 24076655
Identification Methods affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ariadne~Cullin, Cullin_Nedd8~IBR
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
and 1 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 776
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024