HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: MSI2H (Q96DH6)
RNA-binding protein Musashi homolog 2 (Musashi-2)
Gene: MSI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 328
+	Hs
		852050 CUL3_HUMAN (1-768): 0: 951: 100.00		ROA3_HUMAN (15-193): 6.74e-76: 239: 41.99
+	Hs
		453344 CUL3_HUMAN (1-768): 0: 951: 100.00		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		201667 CUL3_HUMAN (1-768): 0: 951: 100.00		MSI1H_HUMAN (1-328): 9.87e-73: 230: 66.94
+	Hs
		1041540 CUL3_HUMAN (1-768): 0: 951: 100.00		HNRPD_HUMAN (6-289): 3.47e-55: 185: 35.21
+	Hs
		1042377 CUL3_HUMAN (1-768): 0: 951: 100.00		ROAA_HUMAN (2-289): 1.19e-53: 180: 36.21
+	Hs
		1031317 CUL3_HUMAN (1-768): 0: 951: 100.00		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		1042258 CUL3_HUMAN (1-768): 0: 951: 100.00		DAZP1_HUMAN (14-189): 4.23e-43: 154: 41.58
+	Hs
		609851 CUL3_HUMAN (1-768): 0: 951: 100.00		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		162039 CUL3_HUMAN (1-768): 0: 951: 100.00		HNRDL_HUMAN (72-204): 1e-19: 91: 28.57
+	Hs
		516505 CUL3_HUMAN (1-768): 0: 951: 100.00		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Hs
		453345 CUL4B_HUMAN (5-768): 0: 779: 36.77		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		1042970 CUL4A_HUMAN (10-768): 0: 791: 38.32		HNRPD_HUMAN (6-289): 3.47e-55: 185: 35.21
+	Hs
		1043188 CUL4A_HUMAN (10-768): 0: 791: 38.32		ROAA_HUMAN (2-289): 1.19e-53: 180: 36.21
+	Hs
		1031318 CUL4A_HUMAN (10-768): 0: 791: 38.32		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		609852 CUL4A_HUMAN (10-768): 0: 791: 38.32		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		609853 CUL4B_HUMAN (5-768): 0: 779: 36.77		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		162040 CUL4A_HUMAN (10-768): 0: 791: 38.32		HNRDL_HUMAN (72-204): 1e-19: 91: 28.57
+	Hs
		516506 CUL4A_HUMAN (10-768): 0: 791: 38.32		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Hs
		162041 CUL4B_HUMAN (5-768): 0: 779: 36.77		HNRDL_HUMAN (72-204): 1e-19: 91: 28.57
+	Hs
		516507 CUL4B_HUMAN (5-768): 0: 779: 36.77		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48