HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: KIF2C (Q99661)
Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK)
Gene: KIF2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005813 - centrosome GO:0005829 - cytosol GO:0007080 - mitotic metaphase chromosome alignment GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 725
+	Hs
		1041608 CUL3_HUMAN (1-768): 0: 951: 100.00		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1042610 CUL3_HUMAN (1-768): 0: 951: 100.00		KI13B_HUMAN (256-671): 1.33e-140: 455: 29.89
+	Hs
		309308 CUL3_HUMAN (1-768): 0: 951: 100.00		KIF4A_HUMAN (250-711): 3.88e-144: 454: 31.06
+	Hs
		855639 CUL3_HUMAN (1-768): 0: 951: 100.00		KIF11_HUMAN (243-722): 3.2e-145: 452: 28.14
+	Hs
		1042996 CUL4A_HUMAN (10-768): 0: 791: 38.32		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		855640 CUL4B_HUMAN (5-768): 0: 779: 36.77		KIF11_HUMAN (243-722): 3.2e-145: 452: 28.14
+	Hs
		229859 CUL1_HUMAN (18-768): 0: 707: 30.57		KIF5C_HUMAN (250-723): 1.5e-143: 446: 26.47
+	Hs
		1041964 CUL3_HUMAN (1-768): 0: 951: 100.00		KI18B_HUMAN (254-588): 3.28e-47: 181: 36.31
+	Hs
		1043083 CUL4A_HUMAN (10-768): 0: 791: 38.32		KIF27_HUMAN (254-642): 6.15e-42: 166: 31.59