HitPredict

Interactor 1: GSC2 (O15499)
Homeobox protein goosecoid-2 (GSC-2) (Homeobox protein goosecoid-like) (GSC-L)
Gene: GSC2

Interactor 2: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 1401
+	Hs
		183064 PAX7_HUMAN (123-199): 4.66e-34: 128: 51.25		KDM6A_HUMAN (1-1401): 0: 1681: 100.00
+	Hs
		183067 PAX6_HUMAN (123-194): 9.8e-34: 125: 48.61		KDM6A_HUMAN (1-1401): 0: 1681: 100.00
+	Hs
		183084 MEOX2_HUMAN (37-191): 6.78e-33: 121: 27.39		KDM6A_HUMAN (1-1401): 0: 1681: 100.00
+	Hs
		183124 Q6FHY5_HUMAN (37-191): 6.64e-33: 121: 27.39		KDM6A_HUMAN (1-1401): 0: 1681: 100.00
+	Hs
		183092 GSC_HUMAN (1-204): 1.63e-31: 116: 33.82		KDM6A_HUMAN (1-1401): 0: 1681: 100.00
+	Dm
		1180627 Q9V490_DROME (102-204): 2.55e-38: 140: 37.62		Q7KJA9_DROME (156-617): 1.46e-44: 178: 14.32