HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	31722399
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1493 Hs			1 474
+	Hs
		1042853 ERCC6_HUMAN (1-1493): 0: 1167: 100.00		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		1042872 ERCC6_HUMAN (1-1493): 0: 1167: 100.00		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		1088500 CHD3_HUMAN (317-1445): 0: 747: 19.86		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Hs
		1066525 CHD7_HUMAN (3-1446): 0: 785: 17.18		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		516638 ERPG3_HUMAN (1-490): 0: 754: 95.73		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		1066276 CHD3_HUMAN (317-1445): 0: 747: 19.86		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		1066410 CHD5_HUMAN (317-1438): 0: 746: 20.05		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		903453 SMCA4_HUMAN (228-1299): 0: 681: 20.36		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Hs
		965260 CHD8_HUMAN (177-1471): 0: 739: 16.90		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		1066307 CHD4_HUMAN (317-1426): 0: 725: 19.25		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		1088371 CHD3_HUMAN (317-1445): 0: 747: 19.86		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		1158933 CHD5_HUMAN (317-1438): 0: 746: 20.05		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		964955 CHD4_HUMAN (317-1426): 0: 725: 19.25		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		1132722 CHD4_HUMAN (317-1426): 0: 725: 19.25		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		903141 SMCA2_HUMAN (228-1388): 0: 684: 18.32		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		903336 SMCA4_HUMAN (228-1299): 0: 681: 20.36		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Ce
		1018638 CHD3_CAEEL (238-1392): 0: 671: 18.59		LIN53_CAEEL (67-296): 5.82e-21: 96.7: 17.01
+	Hs
		243613 SMCA5_HUMAN (381-1322): 0: 670: 23.45		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		903169 SMCA2_HUMAN (228-1388): 0: 684: 18.32		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		243650 SMCA5_HUMAN (381-1322): 0: 670: 23.45		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08