HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: ASB2 (Q96Q27)
Ankyrin repeat and SOCS box protein 2 (ASB-2)
Gene: ASB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36688959
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0016567 - protein ubiquitination GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 759 Hs			1 635
+	Hs
		1021398 CUL4A_HUMAN (1-759): 0: 963: 100.00		ANK3_HUMAN (2-356): 3.48e-96: 326: 21.41
+	Hs
		1041153 CUL1_HUMAN (59-759): 0: 745: 30.55		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Hs
		1041441 CUL2_HUMAN (51-759): 0: 710: 27.00		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Hs
		1021397 CUL3_HUMAN (32-759): 0: 814: 38.23		ANK3_HUMAN (2-356): 3.48e-96: 326: 21.41
+	Hs
		556700 CUL3_HUMAN (32-759): 0: 814: 38.23		ANK1_HUMAN (162-614): 8.21e-91: 310: 21.63
+	Hs
		1274023 CUL5_HUMAN (59-759): 0: 589: 24.94		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Hs
		1043332 CUL4A_HUMAN (1-759): 0: 963: 100.00		ASB3_HUMAN (412-568): 1.18e-15: 81.9: 15.66
+	Hs
		1042054 CUL3_HUMAN (32-759): 0: 814: 38.23		ANR52_HUMAN (4-268): 3.63e-41: 162: 15.56
+	Hs
		1274043 CUL5_HUMAN (59-759): 0: 589: 24.94		TNKS2_HUMAN (21-628): 1.28e-110: 360: 16.55
+	Hs
		166925 CUL3_HUMAN (32-759): 0: 814: 38.23		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		63602 CUL5_HUMAN (59-759): 0: 589: 24.94		ASB14_HUMAN (63-360): 5.02e-50: 185: 20.58
+	Hs
		1264009 CUL5_HUMAN (59-759): 0: 589: 24.94		ASB15_HUMAN (239-568): 8.71e-48: 178: 17.16
+	Hs
		1274095 CUL5_HUMAN (59-759): 0: 589: 24.94		ASB3_HUMAN (412-568): 1.18e-15: 81.9: 15.66