HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: CSN7B (Q9H9Q2)
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)
Gene: COPS7B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	28514442, 33961781, 37091236, 31973889, 16964240, 17079684, 18606781, 21145461, 19295130
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 759 Hs			1 264
+	Hs
		1043598 CUL4B_HUMAN (10-759): 0: 927: 82.31		CSN7B_HUMAN (1-264): 3.34e-107: 312: 100.00
+	Hs
		1043276 CUL4A_HUMAN (1-759): 0: 963: 100.00		CSN7A_HUMAN (1-262): 5.81e-89: 266: 57.30
+	Hs
		1043630 CUL4B_HUMAN (10-759): 0: 927: 82.31		CSN7A_HUMAN (1-262): 5.81e-89: 266: 57.30
+	Hs
		1042568 CUL3_HUMAN (32-759): 0: 814: 38.23		CSN7B_HUMAN (1-264): 3.34e-107: 312: 100.00
+	Hs
		1042750 CUL3_HUMAN (32-759): 0: 814: 38.23		CSN7A_HUMAN (1-262): 5.81e-89: 266: 57.30
+	Hs
		1041205 CUL1_HUMAN (59-759): 0: 745: 30.55		CSN7B_HUMAN (1-264): 3.34e-107: 312: 100.00
+	Hs
		1041468 CUL2_HUMAN (51-759): 0: 710: 27.00		CSN7B_HUMAN (1-264): 3.34e-107: 312: 100.00
+	Hs
		1041247 CUL1_HUMAN (59-759): 0: 745: 30.55		CSN7A_HUMAN (1-262): 5.81e-89: 266: 57.30
+	Hs
		1041487 CUL2_HUMAN (51-759): 0: 710: 27.00		CSN7A_HUMAN (1-262): 5.81e-89: 266: 57.30
+	Ce
		1088884 CUL3_CAEEL (35-759): 0: 740: 33.72		EIF3M_CAEEL (5-216): 2.17e-46: 161: 21.36
+	Hs
		1274053 CUL5_HUMAN (59-759): 0: 589: 24.94		CSN7B_HUMAN (1-264): 3.34e-107: 312: 100.00
+	Hs
		1274073 CUL5_HUMAN (59-759): 0: 589: 24.94		CSN7A_HUMAN (1-262): 5.81e-89: 266: 57.30