Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A
Interactor 2: CRBN (Q96SW2)
Protein cereblon
Gene: CRBN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26231201, 25860244, 27142104, 23983124, 26990986, 27294876, 28514442, 24292625, 32132601, 32235678, 33961781, 20223979, 31973889, 16964240, 21145461, 24292623 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
