HitPredict

Interactor 1: RAB32 (Q13637)
Ras-related protein Rab-32
Gene: RAB32

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 25360523, 31552791
Identification Methods anti bait coimmunoprecipitation, pull down, fluorescence polarization spectroscopy, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Roc
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005764 - lysosome
and 4 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 225
Hs

1 2527
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024