Protein: EF3B
Elongation factor 3B (EF-3B) (EC 3.6.4.-) (Eukaryotic elongation factor 3B) (eEF3) (Homolog of EF-3) (Translation elongation factor 3B)

Gene: EF3B, HEF3
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P53978

Gene Ontology (top 5):
GO:0002182 - cytoplasmic translational elongation
GO:0003723 - RNA binding
GO:0003746 - translation elongation factor activity
GO:0005524 - ATP binding
GO:0006414 - translational elongation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

574597

YAK1
Dual specificity protein kinase YAK1

1

6

High-throughput

0.691

High

850135

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

7

High-throughput

0.585

High

750748

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.536

High

802888

DBP8
ATP-dependent RNA helicase DBP8

1

9

High-throughput

0.536

High

802963

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.513

High

823136

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.513

High

919638

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.513

High

678785

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

1

High-throughput

0.489

High

684637

CDC20
APC/C activator protein CDC20

1

8

High-throughput

0.489

High

925477

CDC14
Tyrosine-protein phosphatase CDC14

1

9

High-throughput

0.489

High

438752

SC160
Protein SCP160

1

4

High-throughput

0.479

High

579871

HSC82
ATP-dependent molecular chaperone HSC82

1

11

High-throughput

0.479

High

679946

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

689099

RL16A
Large ribosomal subunit protein uL13A

1

4

High-throughput

0.479

High

897487

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.479

High

925481

RUVB1
RuvB-like protein 1

1

9

High-throughput

0.479

High

545869

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

670997

SIS1
Protein SIS1

1

10

High-throughput

0.437

High

707873

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.437

High

709915

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

745833

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

3

High-throughput

0.437

High

747987

SMY2
Protein SMY2

1

3

High-throughput

0.437

High

806336

KOG1
Target of rapamycin complex 1 subunit KOG1

1

2

Small-scale

0.437

High

806785

RPN10
26S proteasome regulatory subunit RPN10

1

6

High-throughput

0.437

High

812552

LAA1
AP-1 accessory protein LAA1

1

5

High-throughput

0.437

High

824927

TM108
Protein TMA108

1

7

High-throughput

0.437

High

826045

ULP2
Ubiquitin-like-specific protease 2

1

3

High-throughput

0.437

High

916398

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

3

High-throughput

0.437

High

925478

ULP1
Ubiquitin-like-specific protease 1

1

3

High-throughput

0.437

High

925480

VPS60
Vacuolar protein-sorting-associated protein 60

1

3

Small-scale

0.437

High

925484

ESA1
Histone acetyltransferase ESA1

1

3

Small-scale

0.437

High

925486

TMA46
Translation machinery-associated protein 46

1

4

High-throughput

0.437

High

509673

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

7

High-throughput

0.407

High

780122

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

1

High-throughput

0.407

High

925479

GCN5
Histone acetyltransferase GCN5

1

10

High-throughput

0.407

High

925485

GPN2
GPN-loop GTPase 2

1

1

High-throughput

0.407

High

454474

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

460997

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.279

Low

651974

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.279

Low

684077

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.279

Low

688811

RFA3
Replication factor A protein 3

1

0

High-throughput

0.279

Low

925482

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

781519

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.249

Low

853604

SCD6
Protein SCD6

1

0

Small-scale

0.249

Low

925483

NVJ2
Nucleus-vacuole junction protein 2

1

0

High-throughput

0.249

Low

925487

GID12
GID complex associated protein 12

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025