HitPredict

Interactor 1: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Interactor 2: OBSCN (Q5VST9)
Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)
Gene: OBSCN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030018 - Z disc GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 280 Hs			1 7968
+	Hs
		234566 PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76		DSCAM_HUMAN (6970-7699): 1.72e-30: 136: 12.31
+	Hs
		816234 LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48		DAPK1_HUMAN (7677-7924): 2.14e-26: 123: 30.42
+	Hs
		279845 LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48		TRIO_HUMAN (5562-5999): 1.29e-22: 111: 24.73
+	Hs
		150542 ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03		DAPK1_HUMAN (7677-7924): 2.14e-26: 123: 30.42
+	Hs
		816266 LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Ce
		136803 Q3S1I9_CAEEL (3-219): 4.02e-45: 155: 27.15		UNC89_CAEEL (3788-3968): 1.2e-09: 68.4: 15.27
+	Hs
		1044559 FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		256085 PDLI7_HUMAN (158-278): 1.55e-32: 126: 24.79		OBSL1_HUMAN (7102-7627): 1.09e-09: 68.4: 10.28
+	Hs
		150606 ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		1151801 ABLM2_HUMAN (3-148): 1.19e-24: 104: 22.93		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		1050732 FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Ce
		107557 G5EFG1_CAEEL (3-150): 2.87e-13: 71.6: 26.00		UNC89_CAEEL (3788-3968): 1.2e-09: 68.4: 15.27