Protein: NHP6B
Non-histone chromosomal protein 6B

Gene: NHP6B
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P11633

Gene Ontology (top 5):
GO:0001195 - maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0006281 - DNA repair
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

547845

TUP1
General transcriptional corepressor TUP1

2

20

Small-scale

0.609

High

402178

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

7

High-throughput

0.588

High

547851

RFA1
Replication factor A protein 1

2

8

High-throughput

0.588

High

547857

BTAF1
TATA-binding protein-associated factor MOT1

2

20

High-throughput

0.588

High

547861

STH1
Nuclear protein STH1/NPS1

2

20

High-throughput

0.588

High

547864

RPC6
DNA-directed RNA polymerase III subunit RPC6

2

1

High-throughput

0.588

High

547865

NCBP1
Nuclear cap-binding protein complex subunit 1

2

2

High-throughput

0.588

High

547868

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

20

High-throughput

0.588

High

547877

RSC8
Chromatin structure-remodeling complex protein RSC8

2

14

High-throughput

0.588

High

547879

ITC1
Imitation switch two complex protein 1

2

3

High-throughput

0.588

High

547887

SFH1
Chromatin structure-remodeling complex subunit SFH1

2

4

High-throughput

0.588

High

547891

RSC58
Chromatin structure-remodeling complex protein RSC58

2

1

High-throughput

0.588

High

547892

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

2

20

High-throughput

0.588

High

547897

RUVB2
RuvB-like protein 2

2

13

High-throughput

0.588

High

547749

NHP6A
Non-histone chromosomal protein 6A

1

16

Small-scale

0.575

High

488582

RIR2
Ribonucleoside-diphosphate reductase small chain 1

2

0

High-throughput

0.563

High

547876

IOC3
ISWI one complex protein 3

2

0

High-throughput

0.563

High

547896

TFC7
Transcription factor tau 55 kDa subunit

2

0

High-throughput

0.563

High

547849

VPS1
Vacuolar protein sorting-associated protein 1

2

4

High-throughput

0.537

High

380933

H2B1
Histone H2B.1

1

20

Small-scale

0.527

High

381378

H2B2
Histone H2B.2

1

20

Small-scale

0.527

High

381822

H4
Histone H4

1

12

Small-scale

0.527

High

408382

GAL4
Regulatory protein GAL4

1

1

Small-scale

0.527

High

419335

H2A1
Histone H2A.1

1

20

Small-scale

0.527

High

419568

H2A2
Histone H2A.2

1

20

Small-scale

0.527

High

547847

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

2

Small-scale

0.527

High

547862

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

2

Small-scale

0.527

High

547869

RT107
Regulator of Ty1 transposition protein 107

1

9

Small-scale

0.527

High

547870

SRP14
Signal recognition particle subunit SRP14

1

1

Small-scale

0.527

High

547872

MED3
Mediator of RNA polymerase II transcription subunit 3

1

1

Small-scale

0.527

High

547875

T2FB
Transcription initiation factor IIF subunit beta

1

1

Small-scale

0.527

High

547882

H3
Histone H3

1

20

Small-scale

0.527

High

547894

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

1

Small-scale

0.527

High

547889

HPA2
Histone acetyltransferase HPA2

1

1

Small-scale

0.501

High

547842

RAP1
DNA-binding protein RAP1

1

1

Small-scale

0.481

High

547846

CBF1
Centromere-binding protein 1

1

15

Small-scale

0.481

High

547848

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

Small-scale

0.481

High

547858

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

Small-scale

0.481

High

547860

SWI3
SWI/SNF complex subunit SWI3

1

20

Small-scale

0.481

High

547866

T2EA
Transcription initiation factor IIE subunit alpha

1

1

Small-scale

0.481

High

547867

T2EB
Transcription initiation factor IIE subunit beta

1

1

Small-scale

0.481

High

547871

ITS3
Phosphatidylinositol 4-phosphate 5-kinase MSS4

1

3

Small-scale

0.481

High

547873

MPH1
ATP-dependent DNA helicase MPH1

1

20

Small-scale

0.481

High

547878

TAF1
Transcription initiation factor TFIID subunit 1

1

2

Small-scale

0.481

High

547880

H1
Histone H1

1

1

Small-scale

0.481

High

547883

MLP1
Protein MLP1

1

10

Small-scale

0.481

High

547884

ULP1
Ubiquitin-like-specific protease 1

1

5

High-throughput

0.481

High

547893

DDC1
DNA damage checkpoint protein 1

1

1

Small-scale

0.481

High

547898

CMR1
DNA damage-binding protein CMR1

1

20

High-throughput

0.481

High

448273

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

2

High-throughput

0.479

High

547844

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.479

High

547850

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

5

High-throughput

0.479

High

547853

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

547854

SPT5
Transcription elongation factor SPT5

1

9

High-throughput

0.479

High

547855

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

547856

TF3B
Transcription factor IIIB 70 kDa subunit

1

4

High-throughput

0.479

High

547859

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

8

High-throughput

0.479

High

547874

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

547881

ORC1
Origin recognition complex subunit 1

1

8

High-throughput

0.479

High

547885

TOM1
E3 ubiquitin-protein ligase TOM1

1

13

High-throughput

0.479

High

547888

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

547895

SCC1
Sister chromatid cohesion protein 1

1

3

High-throughput

0.479

High

525753

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

543606

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

547886

RUVB1
RuvB-like protein 1

1

13

High-throughput

0.445

High

394017

EFTU
Elongation factor Tu, mitochondrial

1

6

Small-scale

0.439

High

427106

RLA0
Large ribosomal subunit protein uL10

1

9

High-throughput

0.407

High

547843

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.407

High

547852

RS3A2
Small ribosomal subunit protein eS1B

1

6

High-throughput

0.407

High

547863

CDC13
Cell division control protein 13

1

0

Small-scale

0.249

Low

547890

TEN1
Telomere length regulation protein TEN1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025