HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.701

The method score is based on:

Property Details
Experiments 10777532, 33438746, 12589049, 16382138
Identification Methods two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 5 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 551
Hs

1 2514
+ Mm
+ Mm
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+ Hs
+ Hs
+ Hs
+ Dm
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+ Mm

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Last updated: 11Aug2025