Protein: MAP1S
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain]

Gene: MAP1S
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q66K74

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0001578 - microtubule bundle formation
GO:0003677 - DNA binding
GO:0003779 - actin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1226599

RASF1
Ras association domain-containing protein 1

6

9

Small-scale

0.738

High

1093123

STK4
Serine/threonine-protein kinase 4

4

9

High-throughput

0.699

High

1097685

STK3
Serine/threonine-protein kinase 3

4

9

High-throughput

0.699

High

1226607

FBW1B
F-box/WD repeat-containing protein 11

4

8

High-throughput

0.686

High

1226582

RASF5
Ras association domain-containing protein 5

3

6

High-throughput

0.669

High

675056

TNR6
Tumor necrosis factor receptor superfamily member 6

3

3

High-throughput

0.667

High

1226579

DBF4B
Protein DBF4 homolog B

3

1

High-throughput

0.667

High

1226611

FBW1A
F-box/WD repeat-containing protein 1A

3

9

High-throughput

0.667

High

1226600

ATG3
Ubiquitin-like-conjugating enzyme ATG3

2

2

High-throughput

0.628

High

1226606

GGA1
ADP-ribosylation factor-binding protein GGA1

2

3

High-throughput

0.628

High

841784

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

2

1

Small-scale

0.625

High

1226594

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

2

10

Small-scale

0.619

High

861193

MAP1B
Microtubule-associated protein 1B

2

12

High-throughput

0.611

High

1226583

LIPH
Lipase member H

3

1

High-throughput

0.609

High

1226613

TPPC1
Trafficking protein particle complex subunit 1

2

0

High-throughput

0.602

High

1123670

DCTN1
Dynactin subunit 1

2

3

High-throughput

0.584

High

155953

SOCS3
Suppressor of cytokine signaling 3

1

11

Small-scale

0.573

High

1226592

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

10

High-throughput

0.571

High

158609

VCY2
Testis-specific basic protein Y 2

1

0

Small-scale

0.558

High

1102185

ATM
Serine-protein kinase ATM

1

7

High-throughput

0.541

High

187100

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.536

High

228595

STRN
Striatin

1

8

High-throughput

0.536

High

281340

GGYF1
GRB10-interacting GYF protein 1

1

6

High-throughput

0.536

High

333045

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.536

High

402947

ANXA1
Annexin A1

1

2

High-throughput

0.536

High

456756

ANXA2
Annexin A2

1

3

High-throughput

0.536

High

731389

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.536

High

1147910

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.536

High

1226572

H2BWT
Histone H2B type W-T

1

20

High-throughput

0.536

High

1226573

RASF3
Ras association domain-containing protein 3

1

6

High-throughput

0.536

High

1226596

RABE2
Rab GTPase-binding effector protein 2

1

7

High-throughput

0.536

High

1226597

CAN10
Calpain-10

1

4

High-throughput

0.536

High

1226601

SPHK1
Sphingosine kinase 1

1

1

High-throughput

0.536

High

1226605

CTNA3
Catenin alpha-3

1

3

High-throughput

0.536

High

830908

CCNF
Cyclin-F

1

3

High-throughput

0.515

High

296786

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

334196

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

442357

GELS
Gelsolin

1

0

High-throughput

0.513

High

963520

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

0

High-throughput

0.513

High

1064572

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1144024

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1226589

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.513

High

1226590

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1226608

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.513

High

1226612

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.513

High

1226603

NLGN3
Neuroligin-3

1

1

Small-scale

0.508

High

1006471

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.501

High

1109296

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.501

High

1226576

KLH34
Kelch-like protein 34

1

2

High-throughput

0.489

High

1226578

NOXO1
NADPH oxidase organizer 1

1

3

High-throughput

0.489

High

1226591

LRC27
Leucine-rich repeat-containing protein 27

1

4

High-throughput

0.489

High

1226614

WIF1
Wnt inhibitory factor 1

1

1

High-throughput

0.489

High

1226615

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

822708

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.481

High

940993

HDAC4
Histone deacetylase 4

1

7

Small-scale

0.481

High

122789

KIF2A
Kinesin-like protein KIF2A

1

2

High-throughput

0.479

High

136913

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

3

High-throughput

0.479

High

170196

AURKA
Aurora kinase A

1

7

High-throughput

0.479

High

241976

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

385842

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.479

High

412084

NTRK1
High affinity nerve growth factor receptor

1

9

High-throughput

0.479

High

529954

TAU
Microtubule-associated protein tau

1

19

High-throughput

0.479

High

588909

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

695694

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

714192

PML
Protein PML

1

17

High-throughput

0.479

High

768412

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

970648

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

1045394

TF65
Transcription factor p65

1

7

High-throughput

0.479

High

1065715

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

17

High-throughput

0.479

High

1100001

TIF1B
Transcription intermediary factor 1-beta

1

18

High-throughput

0.479

High

1106574

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.479

High

1113372

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1138307

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1145474

RBBP5
Retinoblastoma-binding protein 5

1

9

High-throughput

0.479

High

1152106

MARE1
Microtubule-associated protein RP/EB family member 1

1

8

High-throughput

0.479

High

1226570

ANR11
Ankyrin repeat domain-containing protein 11

1

9

High-throughput

0.479

High

1226577

FBX22
F-box only protein 22

1

3

High-throughput

0.479

High

1226585

ARHG2
Rho guanine nucleotide exchange factor 2

1

3

Small-scale

0.479

High

1226587

AURKB
Aurora kinase B

1

7

High-throughput

0.479

High

1226588

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1226598

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

1226602

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1226609

MARE3
Microtubule-associated protein RP/EB family member 3

1

8

High-throughput

0.479

High

1178194

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1226575

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1226593

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

255071

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

1226581

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

1

Small-scale

0.445

High

106100

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

1226571

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

1226584

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.437

High

1226595

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

1226604

HECW2
E3 ubiquitin-protein ligase HECW2

1

8

High-throughput

0.437

High

1064994

FGL1
Fibrinogen-like protein 1

3

0

High-throughput

0.347

High

1226580

F174A
Membrane protein FAM174A

2

0

High-throughput

0.328

High

870049

KCNJ6
G protein-activated inward rectifier potassium channel 2

1

0

High-throughput

0.282

High

1006259

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.279

Low

1210045

CF136
Uncharacterized protein C6orf136

1

0

High-throughput

0.279

Low

1226574

CPNE9
Copine-9

1

0

High-throughput

0.279

Low

1226586

ELMD3
ELMO domain-containing protein 3

1

0

High-throughput

0.279

Low

1226610

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.279

Low

516921

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025