HitPredict

Interactor 1: SRBS1 (G5EC32)
Sorbin and SH3 domain-containing protein 1 homolog
Gene: sorb-1

Interactor 2: SRC1 (G5EE56)
Tyrosine protein-kinase src-1 (EC 2.7.10.2) (SRC oncogene related protein 1)
Gene: src-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1005 Ce			1 533
+	Hs
		411800 DLG5_HUMAN (269-1002): 5.73e-41: 166: 12.50		LCK_HUMAN (1-530): 3.31e-180: 518: 43.88
+	Hs
		433909 DLG5_HUMAN (269-1002): 5.73e-41: 166: 12.50		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Hs
		411715 SPTN1_HUMAN (456-964): 1.24e-34: 146: 13.37		LCK_HUMAN (1-530): 3.31e-180: 518: 43.88
+	Hs
		235462 VINEX_HUMAN (357-1004): 2.66e-41: 164: 17.74		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Hs
		433753 SPTN1_HUMAN (456-964): 1.24e-34: 146: 13.37		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Hs
		235483 VINEX_HUMAN (357-1004): 2.66e-41: 164: 17.74		ABL2_HUMAN (11-525): 3.44e-162: 493: 36.94
+	Hs
		298944 SRBS2_HUMAN (80-1004): 1.44e-36: 151: 14.96		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Hs
		337470 SPTN1_HUMAN (456-964): 1.24e-34: 146: 13.37		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Hs
		298959 SRBS2_HUMAN (80-1004): 1.44e-36: 151: 14.96		ABL2_HUMAN (11-525): 3.44e-162: 493: 36.94
+	Hs
		523130 SRBS1_HUMAN (878-1003): 1.56e-20: 100: 32.54		SRC_HUMAN (1-530): 0: 544: 48.45
+	Hs
		523022 SPD2A_HUMAN (638-1005): 2.42e-20: 99.4: 11.33		SRC_HUMAN (1-530): 0: 544: 48.45
+	Hs
		412329 SH3G3_HUMAN (800-1003): 2.06e-20: 96: 14.22		FYN_HUMAN (1-530): 0: 547: 49.26
+	Hs
		412328 SH3G2_HUMAN (878-1003): 1.41e-18: 90.4: 22.22		FYN_HUMAN (1-530): 0: 547: 49.26
+	Hs
		412296 SH3K1_HUMAN (608-751): 5.46e-13: 75.1: 15.19		FYN_HUMAN (1-530): 0: 547: 49.26
+	Hs
		433732 MYO1E_HUMAN (546-740): 2.69e-18: 92.9: 15.00		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Hs
		337548 SRBS1_HUMAN (878-1003): 1.56e-20: 100: 32.54		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Hs
		411817 SH3K1_HUMAN (608-751): 5.46e-13: 75.1: 15.19		LCK_HUMAN (1-530): 3.31e-180: 518: 43.88
+	Hs
		433781 ITSN1_HUMAN (266-1004): 5.36e-14: 79: 11.73		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Hs
		275157 GRAP2_HUMAN (538-742): 9.87e-16: 81.7: 15.61		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Hs
		337526 SH3K1_HUMAN (608-751): 5.46e-13: 75.1: 15.19		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43