Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C
Interactor 2: KCNE2 (Q9Y6J6)
Potassium voltage-gated channel subfamily E member 2 (MinK-related peptide 1) (Minimum potassium ion channel-related peptide 1) (Potassium channel subunit beta MiRP1)
Gene: KCNE2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.90 | 0.708 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24681347 |
| Identification Methods | affinity chromatography technology, pull down, fluorescent resonance energy transfer |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ISK_Channel~Ion_trans |
| Common GO terms | GO:0005886 - plasma membrane GO:0086002 - cardiac muscle cell action potential involved in contraction GO:0086091 - regulation of heart rate by cardiac conduction |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
