HitPredict

Interactor 1: KPCT (Q04759)
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)
Gene: PRKCQ

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.683

The method score is based on:

Property Details
Experiments 17588663
Identification Methods two hybrid, anti bait coimmunoprecipitation, protein kinase assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~Pkinase, C1_1~Pkinase_C, PB1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 706
Hs

1 592
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Service provided by Combinatics, Japan

Last updated: 11Aug2025