HitPredict

Interactor 1: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26318153
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 482
+	Hs
		1030228 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1031497 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		516742 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030438 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		852040 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030211 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		516494 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1048071 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Dm
		1249158 Q9VBQ1_DROME (25-355): 9.19e-51: 180: 26.29		Q8SYC0_DROME (94-414): 4.26e-53: 184: 14.72
+	Sc
		376881 PABP_YEAST (61-266): 4.09e-40: 150: 20.48		BRE5_YEAST (9-419): 2.98e-56: 197: 15.59
+	Dm
		995770 SQD_DROME (78-264): 4.23e-42: 151: 42.55		Q8SYC0_DROME (94-414): 4.26e-53: 184: 14.72
+	Hs
		1048160 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Dm
		1213098 Q8IMS8_DROME (25-355): 5.99e-51: 181: 26.29		Q8IP90_DROME (199-415): 2.87e-24: 108: 12.05
+	Hs
		162101 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1272085 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Dm
		137654 SQD_DROME (78-264): 4.23e-42: 151: 42.55		O02374_DROME (199-415): 6.73e-25: 109: 12.05
+	Hs
		852118 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1031413 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		516621 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		609979 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63