Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 26638075, 34079125, 26496610, 27173435, 35271311, 17828277, 24997520
Identification Methods proximity labelling technology, affinity chromatography technology, isothermal titration calorimetry, molecular sieving, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAP_GLY~EB1
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005874 - microtubule
GO:0019901 - protein kinase binding
and 6 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 268
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024