Interactor 1: ZP2 (Q05996)
Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2]
Gene: ZP2
Interactor 2: ZP4 (Q12836)
Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4]
Gene: ZP4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30810869 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Trefoil~Zona_pellucida, Zona_pellucida~Zona_pellucida |
| Common GO terms | GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0007339 - binding of sperm to zona pellucida GO:0032190 - acrosin binding GO:0035804 - structural constituent of egg coat and 2 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
