HitPredict
Protein: ZP4
Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4]

Gene: ZP4
Organism: Homo sapiens
Interactions: 14
UniProt ID: Q12836

Gene Ontology (top 5):
GO:0002922 - positive regulation of humoral immune response
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007339 - binding of sperm to zona pellucida
GO:0032190 - acrosin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

1086950

 ZP4
Zona pellucida sperm-binding protein 4

1

10

Small-scale

 0.701

High

640662

 ZP3
Zona pellucida sperm-binding protein 3

1

10

Small-scale

 0.575

High

954066

 ZP1
Zona pellucida sperm-binding protein 1

1

10

Small-scale

 0.575

High

1053184

 ZP2
Zona pellucida sperm-binding protein 2

1

10

Small-scale

 0.575

High

521064

 ACRO
Acrosin

1

5

Small-scale

 0.501

High

445848

 ENOA
Alpha-enolase

1

2

Small-scale

 0.479

High

573081

 KPYM
Pyruvate kinase PKM

1

2

Small-scale

 0.479

High

636844

 GSTM3
Glutathione S-transferase Mu 3

1

1

Small-scale

 0.470

High

402585

 ALDOA
Fructose-bisphosphate aldolase A

1

0

Small-scale

 0.458

High

156262

 G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

2

Small-scale

 0.437

High

788302

 GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

2

Small-scale

 0.437

High

949143

 TPIS
Triosephosphate isomerase

1

1

Small-scale

 0.437

High

1086951

 ODFP2
Outer dense fiber protein 2

1

2

Small-scale

 0.437

High

Service provided by Combinatics, Japan

Last updated: 11Aug2025