HitPredict

Interactor 1: MRD1 (Q06106)
Multiple RNA-binding domain-containing protein 1
Gene: MRD1

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	23193268
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 887 Sc			1 459
+	Hs
		550311 PAP1L_HUMAN (1-429): 4.17e-43: 168: 12.64		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Hs
		1197178 PAP1L_HUMAN (1-429): 4.17e-43: 168: 12.64		PABP3_HUMAN (175-459): 2.01e-55: 196: 14.58
+	Hs
		550097 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Hs
		550262 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		PABP4_HUMAN (175-459): 2.2e-57: 202: 13.54
+	Hs
		550464 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		PABP3_HUMAN (175-459): 2.01e-55: 196: 14.58
+	Hs
		1102095 PABP3_HUMAN (3-346): 1.61e-21: 102: 12.64		PABP4_HUMAN (175-459): 2.2e-57: 202: 13.54
+	Hs
		506129 PABP4_HUMAN (759-887): 9.81e-20: 96.4: 17.65		PAB4L_HUMAN (175-459): 1.04e-51: 180: 15.28
+	Hs
		550346 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		PABP2_HUMAN (252-400): 7.94e-43: 155: 25.49
+	Sc
		403611 PABP_YEAST (2-348): 5.32e-21: 100: 12.68		NOP13_YEAST (27-400): 8.64e-41: 152: 17.73
+	Hs
		550137 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		TIA1_HUMAN (273-459): 1.48e-33: 131: 12.23
+	Mm
		710979 PABP1_MOUSE (2-327): 1.37e-24: 111: 13.64		TIA1_MOUSE (273-459): 1.48e-33: 131: 12.23
+	Hs
		550250 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		ELAV2_HUMAN (37-360): 2.42e-31: 125: 11.49
+	Hs
		1101971 PABP4_HUMAN (759-887): 9.81e-20: 96.4: 17.65		ELAV1_HUMAN (154-360): 6.07e-33: 128: 14.23
+	Hs
		1090216 PABP4_HUMAN (759-887): 9.81e-20: 96.4: 17.65		ELAV2_HUMAN (37-360): 2.42e-31: 125: 11.49
+	Hs
		550237 PABP1_HUMAN (2-327): 1.55e-24: 111: 13.33		TIAR_HUMAN (8-280): 1.16e-10: 64.9: 8.03