Protein: PABP2
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)

Gene: PABP2, PABPN1
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q86U42

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126977

RBM39
RNA-binding protein 39

2

18

High-throughput

0.789

High

775173

FUS
RNA-binding protein FUS

2

20

High-throughput

0.754

High

1066698

NCBP1
Nuclear cap-binding protein subunit 1

2

8

Small-scale

0.754

High

1287811

KAT6A
Histone acetyltransferase KAT6A

2

14

Small-scale

0.754

High

485235

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

Small-scale

0.740

High

1287823

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

20

Small-scale

0.740

High

576448

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

19

High-throughput

0.691

High

994632

YBOX1
Y-box-binding protein 1

1

20

Small-scale

0.691

High

1160185

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

17

High-throughput

0.691

High

1287804

RBM45
RNA-binding protein 45

1

19

High-throughput

0.691

High

1287817

PABP5
Polyadenylate-binding protein 5

1

18

High-throughput

0.691

High

1062531

DHX9
ATP-dependent RNA helicase A

3

15

Small-scale

0.650

High

1111074

SNW1
SNW domain-containing protein 1

2

2

Small-scale

0.649

High

550346

PABP1
Polyadenylate-binding protein 1

1

15

Small-scale

0.646

High

260131

BRD4
Bromodomain-containing protein 4

3

9

High-throughput

0.640

High

372447

MYC
Myc proto-oncogene protein

3

19

High-throughput

0.640

High

401073

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

13

High-throughput

0.618

High

472861

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.618

High

478104

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.618

High

685628

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

High-throughput

0.618

High

897887

CDK9
Cyclin-dependent kinase 9

1

17

High-throughput

0.618

High

1033045

EWS
RNA-binding protein EWS

1

17

High-throughput

0.618

High

1096076

TADBP
TAR DNA-binding protein 43

1

20

Small-scale

0.618

High

1120222

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

High-throughput

0.618

High

1194195

LARP7
La-related protein 7

1

20

High-throughput

0.618

High

1287826

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.618

High

1287831

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

17

High-throughput

0.618

High

1287841

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.618

High

1287848

RBM8A
RNA-binding protein 8A

1

19

High-throughput

0.618

High

335145

ARI2
E3 ubiquitin-protein ligase ARIH2

2

16

Small-scale

0.584

High

346012

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

18

High-throughput

0.584

High

911627

NCBP2
Nuclear cap-binding protein subunit 2

1

17

High-throughput

0.575

High

1245646

LARP1
La-related protein 1

1

20

Small-scale

0.575

High

1287834

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.575

High

1287849

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

20

Small-scale

0.575

High

430092

JUN
Transcription factor Jun

2

8

High-throughput

0.571

High

703956

DUS1
Dual specificity protein phosphatase 1

2

4

High-throughput

0.571

High

765668

BMI1
Polycomb complex protein BMI-1

2

14

High-throughput

0.571

High

1023023

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

2

9

High-throughput

0.571

High

1279137

RHG22
Rho GTPase-activating protein 22

2

5

High-throughput

0.571

High

461654

HS90A
Heat shock protein HSP 90-alpha

1

10

Small-scale

0.561

High

157564

CTRO
Citron Rho-interacting kinase

1

13

High-throughput

0.553

High

1198585

NCBP3
Nuclear cap-binding protein subunit 3

2

5

High-throughput

0.552

High

287958

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

2

High-throughput

0.541

High

166536

BACH1
Transcription regulator protein BACH1

1

6

High-throughput

0.536

High

271540

ATG13
Autophagy-related protein 13

1

2

High-throughput

0.536

High

272964

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

2

High-throughput

0.536

High

471116

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

4

High-throughput

0.536

High

574347

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

5

High-throughput

0.536

High

1065270

SSRP1
FACT complex subunit SSRP1

1

11

High-throughput

0.536

High

1109467

ATR
Serine/threonine-protein kinase ATR

1

4

High-throughput

0.536

High

1112576

CUL1
Cullin-1

1

20

High-throughput

0.536

High

1112896

CUL2
Cullin-2

1

20

High-throughput

0.536

High

1113557

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1136031

CND2
Condensin complex subunit 2

1

2

High-throughput

0.536

High

1149112

SF3A1
Splicing factor 3A subunit 1

1

7

High-throughput

0.536

High

1287802

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

13

High-throughput

0.536

High

1287806

NUP37
Nucleoporin Nup37

1

8

High-throughput

0.536

High

1287813

CSN5
COP9 signalosome complex subunit 5

1

7

High-throughput

0.536

High

1287815

CUL5
Cullin-5

1

20

High-throughput

0.536

High

1287819

RBM33
RNA-binding protein 33

1

7

High-throughput

0.536

High

1287836

DDX21
Nucleolar RNA helicase 2

1

19

High-throughput

0.536

High

1287838

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

4

High-throughput

0.536

High

1287846

EMC9
ER membrane protein complex subunit 9

1

3

High-throughput

0.536

High

1287829

ACE2
Angiotensin-converting enzyme 2

2

5

High-throughput

0.533

High

349143

LATS1
Serine/threonine-protein kinase LATS1

1

9

Small-scale

0.527

High

1137370

SUZ12
Polycomb protein SUZ12

1

4

High-throughput

0.515

High

192604

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

1287847

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.513

High

903403

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

13

Small-scale

0.508

High

1287840

DNJB4
DnaJ homolog subfamily B member 4

1

5

Small-scale

0.508

High

185821

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

691189

1433T
14-3-3 protein theta

1

11

High-throughput

0.501

High

1287803

CARM1
Histone-arginine methyltransferase CARM1

1

18

Small-scale

0.501

High

1287814

TNPO1
Transportin-1

1

4

Small-scale

0.501

High

226566

TLX2
T-cell leukemia homeobox protein 2

1

2

High-throughput

0.500

High

776095

SOX5
Transcription factor SOX-5

1

12

High-throughput

0.500

High

776211

SOX6
Transcription factor SOX-6

1

17

High-throughput

0.500

High

1287812

RENT1
Regulator of nonsense transcripts 1

1

15

Small-scale

0.500

High

1091529

DLG1
Disks large homolog 1

1

0

High-throughput

0.480

High

65911

RHG42
Rho GTPase-activating protein 42

1

6

High-throughput

0.479

High

129225

MEN1
Menin

1

4

High-throughput

0.479

High

223155

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.479

High

252467

DIAP1
Protein diaphanous homolog 1

1

3

High-throughput

0.479

High

285343

EED
Polycomb protein EED

1

12

High-throughput

0.479

High

293945

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

315739

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

319877

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

352480

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.479

High

375672

RASK
GTPase KRas

1

6

High-throughput

0.479

High

406341

MYCN
N-myc proto-oncogene protein

1

19

High-throughput

0.479

High

480205

RU1C
U1 small nuclear ribonucleoprotein C

1

4

High-throughput

0.479

High

508219

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

16

High-throughput

0.479

High

542093

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.479

High

551133

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.479

High

606884

CEBPB
CCAAT/enhancer-binding protein beta

1

7

High-throughput

0.479

High

674226

BRD2
Bromodomain-containing protein 2

1

12

High-throughput

0.479

High

698315

MAP4
Microtubule-associated protein 4

1

15

High-throughput

0.479

High

761743

HSP74
Heat shock 70 kDa protein 4

1

5

Small-scale

0.479

High

766663

PHB1
Prohibitin 1

1

11

High-throughput

0.479

High

872482

SOX2
Transcription factor SOX-2

1

13

High-throughput

0.479

High

895929

F10A1
Hsc70-interacting protein

1

6

Small-scale

0.479

High

904887

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

965062

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.479

High

979906

H4
Histone H4

1

5

High-throughput

0.479

High

990426

1433Z
14-3-3 protein zeta/delta

1

11

High-throughput

0.479

High

995671

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

1024667

VIGLN
Vigilin

1

20

High-throughput

0.479

High

1050467

UBE3A
Ubiquitin-protein ligase E3A

1

11

High-throughput

0.479

High

1067472

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

1092170

NFX1
Transcriptional repressor NF-X1

1

5

High-throughput

0.479

High

1093653

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

17

High-throughput

0.479

High

1106987

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1121260

TRI14
Tripartite motif-containing protein 14

1

6

High-throughput

0.479

High

1137823

TNIP1
TNFAIP3-interacting protein 1

1

13

High-throughput

0.479

High

1140181

ARHG6
Rho guanine nucleotide exchange factor 6

1

5

High-throughput

0.479

High

1140496

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1141196

BRD3
Bromodomain-containing protein 3

1

11

High-throughput

0.479

High

1155510

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.479

High

1199325

GLE1
mRNA export factor GLE1

1

9

High-throughput

0.479

High

1215691

RC3H1
Roquin-1

1

14

High-throughput

0.479

High

1254453

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

1287801

ZCH18
Zinc finger CCCH domain-containing protein 18

1

12

High-throughput

0.479

High

1287808

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

5

High-throughput

0.479

High

1287809

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.479

High

1287816

FUBP1
Far upstream element-binding protein 1

1

20

High-throughput

0.479

High

1287820

CI072
Guanine nucleotide exchange factor C9orf72

1

5

High-throughput

0.479

High

1287822

RANB9
Ran-binding protein 9

1

8

High-throughput

0.479

High

1287824

ANM1
Protein arginine N-methyltransferase 1

1

18

High-throughput

0.479

High

1287825

CENPO
Centromere protein O

1

1

High-throughput

0.479

High

1287828

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.479

High

1287830

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1287833

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

1287835

ENY2
Transcription and mRNA export factor ENY2

1

2

High-throughput

0.479

High

1287837

BCLF1
Bcl-2-associated transcription factor 1

1

6

High-throughput

0.479

High

1287839

ITSN2
Intersectin-2

1

3

High-throughput

0.479

High

1287843

FZR1
Fizzy-related protein homolog

1

14

High-throughput

0.479

High

1287844

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

Small-scale

0.479

High

188922

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.458

High

442757

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.458

High

581682

MYOD1
Myoblast determination protein 1

1

0

Small-scale

0.458

High

64405

A6H8W8
Intersectin 2

1

3

High-throughput

0.445

High

141552

DDX3X
ATP-dependent RNA helicase DDX3X

1

13

Small-scale

0.445

High

402961

ANXA1
Annexin A1

1

4

Small-scale

0.445

High

447174

NPM
Nucleophosmin

1

4

Small-scale

0.445

High

684293

DDX6
Probable ATP-dependent RNA helicase DDX6

1

20

Small-scale

0.445

High

952226

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

967829

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

9

High-throughput

0.445

High

1089459

ILF2
Interleukin enhancer-binding factor 2

1

7

Small-scale

0.445

High

1089734

ILF3
Interleukin enhancer-binding factor 3

1

15

Small-scale

0.445

High

1130319

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

10

High-throughput

0.445

High

1287807

THOC2
THO complex subunit 2

1

8

High-throughput

0.445

High

1287821

CEP63
Centrosomal protein of 63 kDa

1

9

High-throughput

0.445

High

1287845

PA2G4
Proliferation-associated protein 2G4

1

4

Small-scale

0.445

High

164374

NRP1
Neuropilin-1

1

3

High-throughput

0.437

High

377633

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

412184

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

418239

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

472089

MET
Hepatocyte growth factor receptor

1

4

High-throughput

0.437

High

488817

FURIN
Furin

1

1

High-throughput

0.437

High

711910

LTK
Leukocyte tyrosine kinase receptor

1

8

High-throughput

0.437

High

774471

BASI
Basigin

1

5

High-throughput

0.437

High

1212262

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.437

High

1213061

RHG21
Rho GTPase-activating protein 21

1

7

High-throughput

0.437

High

1226981

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.437

High

1287805

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.437

High

1287810

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1287818

RNF31
E3 ubiquitin-protein ligase RNF31

1

17

High-throughput

0.437

High

1287842

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.437

High

213186

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.407

High

1210892

CE170
Centrosomal protein of 170 kDa

1

6

High-throughput

0.407

High

1253139

NBEL2
Neurobeachin-like protein 2

1

13

High-throughput

0.407

High

1287832

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.407

High

1256693

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

1060714

SOS2
Son of sevenless homolog 2

1

0

High-throughput

0.249

Low

1273765

NIPA1
Magnesium transporter NIPA1

1

0

High-throughput

0.232

Low

1287827

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025