HitPredict

Interactor 1: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK

Interactor 2: TTC9C (Q8N5M4)
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)
Gene: TTC9C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 659 Hs			1 171
+	Hs
		124715 FYN_HUMAN (155-653): 0: 527: 34.35		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		440543 FYN_HUMAN (155-653): 0: 527: 34.35		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		124719 YES_HUMAN (133-653): 1.37e-179: 522: 32.77		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		124727 SRC_HUMAN (169-653): 4.54e-178: 518: 35.34		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		463084 YES_HUMAN (133-653): 1.37e-179: 522: 32.77		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		440047 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		PPID_HUMAN (1-171): 7.12e-38: 134: 23.98
+	Hs
		124723 FGR_HUMAN (152-653): 1.61e-172: 504: 32.56		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		440145 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		TTC9C_HUMAN (1-171): 8.61e-39: 131: 100.00
+	Hs
		440035 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		FKBP4_HUMAN (2-170): 5.52e-35: 128: 23.67
+	Hs
		486691 FGR_HUMAN (152-653): 1.61e-172: 504: 32.56		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		124714 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		440199 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		TANC1_HUMAN (9-156): 2.76e-33: 125: 23.65
+	Hs
		463751 LYN_HUMAN (154-653): 1.19e-167: 490: 34.92		TANC1_HUMAN (9-156): 2.76e-33: 125: 23.65
+	Hs
		124754 BLK_HUMAN (156-653): 3.08e-164: 482: 35.98		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		902833 BLK_HUMAN (156-653): 3.08e-164: 482: 35.98		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30