Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: RUBIC (Q92622)
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron)
Gene: RUBCN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 29587298, 19270693, 33961781, 19270696, 26496610, 25891078, 26876213, 27621469, 19372752, 31373534, 31696776, 33977871, 23954414, 34386498, 20562859, 24980960, 22423967, 21062745, 22493499, 25594178 and 1 others

more...

Identification Methods affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006914 - autophagy
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 450
Hs

1 972
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024