Protein: PNPH
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)

Gene: PNPH, PNP
Organism: Homo sapiens
Interactions: 70
UniProt ID: P00491

Gene Ontology (top 5):
GO:0000255 - allantoin metabolic process
GO:0001882 - nucleoside binding
GO:0002060 - purine nucleobase binding
GO:0004731 - purine-nucleoside phosphorylase activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

336981

PNPH
Purine nucleoside phosphorylase

6

5

Small-scale

0.935

High

253518

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

2

1

High-throughput

0.576

High

226196

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

337039

SHOC2
Leucine-rich repeat protein SHOC-2

2

0

High-throughput

0.547

High

337003

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.536

High

337016

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.536

High

337022

CDKL3
Cyclin-dependent kinase-like 3

1

1

High-throughput

0.536

High

336984

P53
Cellular tumor antigen p53

1

0

High-throughput

0.518

High

336990

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

336985

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

337031

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.515

High

201160

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

337041

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

Small-scale

0.501

High

337007

APLP1
Amyloid beta precursor like protein 1

1

1

High-throughput

0.494

High

337033

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

0

High-throughput

0.493

High

148025

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

0

High-throughput

0.493

High

336986

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.493

High

336992

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.493

High

336994

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.493

High

337011

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.493

High

337015

TGIF1
Homeobox protein TGIF1

1

0

High-throughput

0.493

High

337025

SORL
Sortilin-related receptor

1

0

High-throughput

0.493

High

337026

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

337040

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.493

High

337034

KDM4C
Lysine-specific demethylase 4C

1

1

High-throughput

0.489

High

329207

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

336991

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

336995

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

337004

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

337006

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

337008

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

337021

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

337024

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

337037

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.479

High

122433

MEN1
Menin

1

0

High-throughput

0.458

High

167793

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

336982

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

336983

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

336987

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

336989

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

336997

RAB4A
Ras-related protein Rab-4A

1

0

High-throughput

0.458

High

336998

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

336999

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

337002

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

337009

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

337010

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

337013

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

337014

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

337023

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

337027

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

337028

OPTN
Optineurin

1

0

High-throughput

0.458

High

337035

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

337019

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.457

High

336993

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

337000

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

337001

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

337020

LMTK1
Serine/threonine-protein kinase LMTK1

1

2

High-throughput

0.437

High

337029

LMTK3
Serine/threonine-protein kinase LMTK3

1

1

High-throughput

0.437

High

336988

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

336996

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

337012

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

Small-scale

0.426

High

337005

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.373

High

337017

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

337032

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.282

High

337038

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.282

High

337018

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

225448

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

337030

DERL1
Derlin-1

1

0

Small-scale

0.249

Low

337036

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024