HitPredict - High confidence protein-protein interactions

Interactor 1: SKR1 (G5ECU1)
Skp1-related protein
Gene: skr-1

Interactor 2: SKR1 (G5ECU1)
Skp1-related protein
Gene: skr-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	38354250, 19123269
Identification Methods	pull down, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Skp1~Skp1_POZ, Skp1_POZ~Skp1_POZ
Common GO terms	GO:0000278 - mitotic cell cycle GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006511 - ubiquitin-dependent protein catabolic process GO:0007399 - nervous system development and 12 others more... GO:0010629 - negative regulation of gene expression GO:0010826 - negative regulation of centrosome duplication GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031647 - regulation of protein stability GO:0043065 - positive regulation of apoptotic process GO:0043518 - negative regulation of DNA damage response, signal transduction by p53 class mediator GO:0046660 - female sex differentiation GO:0090128 - regulation of synapse maturation GO:0097602 - cullin family protein binding GO:1902230 - negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage GO:1905806 - regulation of synapse pruning
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1	176
Ce

1	176

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Last updated: 15 Jul 2024