Interactor 1: SKR1 (G5ECU1)
Skp1-related protein
Gene: skr-1

Interactor 2: CUL1 (Q17389)
Cullin-1 (CUL-1) (Abnormal cell lineage protein 19)
Gene: cul-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.889

The method score is based on:

Property Details
Experiments 28739890, 11864567, 11864566, 18718460
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Skp1_POZ
Common GO terms GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0010826 - negative regulation of centrosome duplication
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 176
Ce

1 780
+ Mm
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Sp
+ At
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024