HitPredict

Interactor 1: KCTD2 (Q14681)
BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2)
Gene: KCTD2

Interactor 2: GBG8 (Q9UK08)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (Gamma-9)
Gene: GNG8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 70
+	Hs
		887108 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		GBG2_HUMAN (2-70): 8.61e-27: 94: 71.01
+	Hs
		229241 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		GBG7_HUMAN (3-70): 1.04e-23: 86.2: 52.94
+	Hs
		1057247 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		GBG12_HUMAN (2-70): 4.08e-23: 84.7: 49.28
+	Hs
		887130 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		GBG2_HUMAN (2-70): 8.61e-27: 94: 71.01
+	Hs
		229248 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		GBG7_HUMAN (3-70): 1.04e-23: 86.2: 52.94
+	Hs
		1348074 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		GBG12_HUMAN (2-70): 4.08e-23: 84.7: 49.28
+	Hs
		887118 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		GBG2_HUMAN (2-70): 8.61e-27: 94: 71.01
+	Hs
		1235390 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		GBG8_HUMAN (1-70): 9.17e-26: 91.3: 100.00
+	Hs
		837679 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		GBG4_HUMAN (2-70): 1.82e-25: 90.9: 60.87
+	Hs
		887112 KCD16_HUMAN (59-183): 6.13e-37: 136: 30.47		GBG2_HUMAN (2-70): 8.61e-27: 94: 71.01
+	Hs
		887120 KCD12_HUMAN (65-167): 3.74e-33: 124: 35.58		GBG2_HUMAN (2-70): 8.61e-27: 94: 71.01