HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: SALL4 (Q9UJQ4)
Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4)
Gene: SALL4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 33283408
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 1053
+	Mm
		1161073 CHD4_MOUSE (1-1900): 0: 1680: 97.80		SALL4_MOUSE (1-1053): 0: 718: 72.51
+	Hs
		1018740 CHD3_HUMAN (23-1905): 0: 1595: 66.89		SALL4_HUMAN (1-1053): 0: 600: 100.00
+	Hs
		1059842 CHD4_HUMAN (1-1912): 0: 1719: 100.00		SALL3_HUMAN (411-649): 1.9e-17: 90.3: 19.92
+	Hs
		1059898 CHD4_HUMAN (1-1912): 0: 1719: 100.00		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83
+	Hs
		1018709 CHD3_HUMAN (23-1905): 0: 1595: 66.89		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83
+	Hs
		1315138 CHD7_HUMAN (3-1678): 0: 805: 23.02		SALL3_HUMAN (411-649): 1.9e-17: 90.3: 19.92
+	Mm
		57187 CHD7_MOUSE (3-1678): 0: 817: 23.03		SALL3_MOUSE (596-797): 2e-12: 73.7: 17.82