HitPredict

Interactor 1: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Interactor 2: RANB3 (Q9H6Z4)
Ran-binding protein 3 (RanBP3)
Gene: RANBP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	35044719
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 876 Hs			1 567
+	Hs
		1060962 IMB1_HUMAN (1-876): 0: 635: 100.00		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		483396 IMB1_HUMAN (1-876): 0: 635: 100.00		RGPD1_HUMAN (237-548): 1.99e-36: 147: 17.30
+	Hs
		152779 IMB1_HUMAN (1-876): 0: 635: 100.00		RGPD8_HUMAN (246-547): 9.23e-36: 145: 16.72
+	Hs
		834746 IMB1_HUMAN (1-876): 0: 635: 100.00		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	Hs
		796746 IMB1_HUMAN (1-876): 0: 635: 100.00		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Sc
		691667 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		NUP2_YEAST (120-512): 1.75e-28: 122: 14.25
+	Sc
		785008 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		YRB1_YEAST (330-515): 9.14e-24: 101: 18.75
+	Sc
		746510 IMB2_YEAST (1-758): 5.92e-112: 366: 13.61		YRB1_YEAST (330-515): 9.14e-24: 101: 18.75
+	Hs
		268632 SF3B1_HUMAN (146-866): 1.96e-78: 279: 12.23		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	Hs
		312202 IPO7_HUMAN (3-848): 8.3e-82: 286: 12.03		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Xl
		1137361 Q5U4V0_XENLA (139-870): 1.72e-27: 121: 13.82		Q6DCU3_XENLA (90-509): 9.76e-57: 198: 14.38
+	Hs
		1273239 TNPO1_HUMAN (125-870): 3.59e-28: 123: 12.21		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		1273208 TNPO1_HUMAN (125-870): 3.59e-28: 123: 12.21		RGPD5_HUMAN (246-548): 1.48e-35: 144: 16.35
+	Sc
		687906 IMB3_YEAST (3-831): 2.12e-34: 144: 16.29		NUP2_YEAST (120-512): 1.75e-28: 122: 14.25
+	Hs
		834809 TNPO1_HUMAN (125-870): 3.59e-28: 123: 12.21		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	Hs
		796783 TNPO1_HUMAN (125-870): 3.59e-28: 123: 12.21		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Hs
		155547 TNPO2_HUMAN (124-869): 4.11e-25: 114: 14.04		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Hs
		127219 IPO5_HUMAN (89-863): 6.82e-13: 75: 10.97		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	Hs
		127208 IPO5_HUMAN (89-863): 6.82e-13: 75: 10.97		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73