HitPredict

Interactor 1: Q149N5 (Q149N5)
DOCK4 protein
Gene: DOCK4

Interactor 2: ELMO2 (Q96JJ3)
Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A)
Gene: ELMO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DOCK_N~PH_12
Common GO terms	GO:0060326 - cell chemotaxis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2011 Hs			1 720
+	Hs
		1230992 DOCK4_HUMAN (1-2011): 0: 2040: 97.56		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1230987 DOCK4_HUMAN (1-2011): 0: 2040: 97.56		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		1230990 DOCK4_HUMAN (1-2011): 0: 2040: 97.56		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Hs
		1050489 DOCK1_HUMAN (2-1759): 0: 1856: 36.31		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Mm
		1206593 DOCK1_MOUSE (2-1853): 0: 1857: 35.11		ELMO2_MOUSE (1-720): 0: 1042: 97.13
+	Hs
		1224227 DOCK3_HUMAN (1-2008): 0: 1822: 53.84		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1050484 DOCK1_HUMAN (2-1759): 0: 1856: 36.31		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Mm
		1207128 DOCK1_MOUSE (2-1853): 0: 1857: 35.11		ELMO1_MOUSE (1-718): 0: 1010: 75.34
+	Hs
		1267934 DOCK2_HUMAN (2-1712): 0: 1814: 36.22		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1224220 DOCK3_HUMAN (1-2008): 0: 1822: 53.84		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		1267020 DOCK2_HUMAN (2-1712): 0: 1814: 36.22		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Mm
		1207130 DOCK2_MOUSE (2-1794): 0: 1810: 35.47		ELMO1_MOUSE (1-718): 0: 1010: 75.34
+	Mm
		1207312 DOCK1_MOUSE (2-1853): 0: 1857: 35.11		ELMO3_MOUSE (1-719): 0: 944: 51.11
+	Hs
		1050487 DOCK1_HUMAN (2-1759): 0: 1856: 36.31		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Hs
		1295265 DOCK5_HUMAN (2-1836): 0: 1742: 34.07		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1224225 DOCK3_HUMAN (1-2008): 0: 1822: 53.84		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Hs
		1267024 DOCK5_HUMAN (2-1836): 0: 1742: 34.07		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		1285559 DOCK5_HUMAN (2-1836): 0: 1742: 34.07		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Dm
		1362934 Q9VCH4_DROME (5-1901): 0: 1578: 28.81		Q9VKB2_DROME (5-718): 0: 839: 44.60
+	Dm
		81396 B7Z0R2_DROME (1-1784): 0: 1569: 37.25		Q9VKB2_DROME (5-718): 0: 839: 44.60