Protein: MYOD1
Myoblast determination protein 1 (Class C basic helix-loop-helix protein 1) (bHLHc1) (Myogenic factor 3) (Myf-3)

Gene: MYOD1
Organism: Homo sapiens
Interactions: 167
UniProt ID: P15172

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

581630

ID1
DNA-binding protein inhibitor ID-1

7

13

Small-scale

0.957

High

581617

TFE2
Transcription factor E2-alpha

5

20

Small-scale

0.934

High

581633

CSRP3
Cysteine and glycine-rich protein 3

2

4

Small-scale

0.821

High

581643

ID2
DNA-binding protein inhibitor ID-2

2

13

Small-scale

0.800

High

581616

ITF2
Transcription factor 4

2

20

Small-scale

0.793

High

223953

TCF21
Transcription factor 21

2

16

High-throughput

0.783

High

581638

LMO4
LIM domain transcription factor LMO4

2

12

High-throughput

0.783

High

581673

FIGLA
Factor in the germline alpha

2

18

High-throughput

0.783

High

581651

EP300
Histone acetyltransferase p300

6

19

Small-scale

0.732

High

581704

CBP
CREB-binding protein

5

20

Small-scale

0.717

High

581706

KAT2B
Histone acetyltransferase KAT2B

5

13

Small-scale

0.702

High

581719

HTF4
Transcription factor 12

1

20

High-throughput

0.691

High

581635

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

4

14

Small-scale

0.676

High

581656

HDAC1
Histone deacetylase 1

3

8

Small-scale

0.667

High

154932

BHE40
Class E basic helix-loop-helix protein 40

1

13

Small-scale

0.647

High

581614

MYOD1
Myoblast determination protein 1

1

16

Small-scale

0.647

High

581728

BHE41
Class E basic helix-loop-helix protein 41

1

13

Small-scale

0.647

High

442570

RB
Retinoblastoma-associated protein

2

5

Small-scale

0.629

High

581622

PAX7
Paired box protein Pax-7

1

5

Small-scale

0.618

High

581627

CUX1
Homeobox protein cut-like 1

1

3

High-throughput

0.618

High

581644

ID3
DNA-binding protein inhibitor ID-3

1

13

Small-scale

0.618

High

581688

MGAP
MAX gene-associated protein

1

3

High-throughput

0.618

High

581732

MLXPL
Carbohydrate-responsive element-binding protein

1

4

Small-scale

0.618

High

581747

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

13

Small-scale

0.618

High

549039

CDK4
Cyclin-dependent kinase 4

2

2

Small-scale

0.614

High

162453

ANM5
Protein arginine N-methyltransferase 5

2

4

Small-scale

0.595

High

278228

NCOR1
Nuclear receptor corepressor 1

2

8

Small-scale

0.595

High

581647

MEF2C
Myocyte-specific enhancer factor 2C

2

7

Small-scale

0.594

High

581640

H31
Histone H3.1

1

0

Small-scale

0.586

High

581674

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

2

4

Small-scale

0.584

High

581684

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

0

High-throughput

0.580

High

581711

FBX32
F-box only protein 32

1

3

Small-scale

0.573

High

581722

MDFI
MyoD family inhibitor

1

2

Small-scale

0.573

High

136199

IFRD1
Interferon-related developmental regulator 1

2

0

Small-scale

0.569

High

216370

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

7

Small-scale

0.561

High

429238

JUN
Transcription factor Jun

1

3

Small-scale

0.561

High

581629

STAT3
Signal transducer and activator of transcription 3

1

3

Small-scale

0.561

High

581632

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

2

Small-scale

0.561

High

581642

RUNX1
Runt-related transcription factor 1

1

6

Small-scale

0.561

High

581679

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

Small-scale

0.561

High

581698

SETD7
Histone-lysine N-methyltransferase SETD7

1

1

Small-scale

0.561

High

581709

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.561

High

581726

AP1M1
AP-1 complex subunit mu-1

2

1

High-throughput

0.553

High

549273

SRF
Serum response factor

1

6

Small-scale

0.552

High

581721

PHB2
Prohibitin-2

1

2

Small-scale

0.552

High

581712

ESPB1
Epididymal sperm-binding protein 1

2

2

Small-scale

0.543

High

138623

IMA4
Importin subunit alpha-4

1

3

High-throughput

0.541

High

581681

SETD3
Actin-histidine N-methyltransferase

1

0

Small-scale

0.537

High

581636

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.529

High

581639

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.518

High

581739

PSME2
Proteasome activator complex subunit 2

1

0

High-throughput

0.518

High

177650

SMAD7
Mothers against decapentaplegic homolog 7

1

4

High-throughput

0.508

High

581655

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.508

High

581620

RXRA
Retinoic acid receptor RXR-alpha

1

8

Small-scale

0.501

High

581623

COT2
COUP transcription factor 2

1

7

Small-scale

0.501

High

581625

RORA
Nuclear receptor ROR-alpha

1

9

Small-scale

0.501

High

581686

CARM1
Histone-arginine methyltransferase CARM1

1

4

Small-scale

0.501

High

581692

MYCD
Myocardin

1

4

Small-scale

0.501

High

581689

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

4

Small-scale

0.484

High

464786

SP1
Transcription factor Sp1

1

4

Small-scale

0.481

High

461107

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.480

High

138966

BCL9
B-cell CLL/lymphoma 9 protein

1

9

High-throughput

0.479

High

154622

ARI1A
AT-rich interactive domain-containing protein 1A

1

8

High-throughput

0.479

High

161404

KMT2D
Histone-lysine N-methyltransferase 2D

1

15

High-throughput

0.479

High

174305

ZN609
Zinc finger protein 609

1

5

High-throughput

0.479

High

180690

TIF1A
Transcription intermediary factor 1-alpha

1

12

High-throughput

0.479

High

194505

KDM6A
Lysine-specific demethylase 6A

1

3

High-throughput

0.479

High

245583

ZEB2
Zinc finger E-box-binding homeobox 2

1

5

High-throughput

0.479

High

261363

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

1

High-throughput

0.479

High

273975

CREST
Calcium-responsive transactivator

1

9

High-throughput

0.479

High

284922

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

2

High-throughput

0.479

High

344859

WIZ
Protein Wiz

1

4

High-throughput

0.479

High

395428

ESR1
Estrogen receptor

1

8

Small-scale

0.479

High

559722

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

12

High-throughput

0.479

High

571861

TRI27
Zinc finger protein RFP

1

4

Small-scale

0.479

High

581615

ZEP1
Zinc finger protein 40

1

4

High-throughput

0.479

High

581618

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.479

High

581619

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

Small-scale

0.479

High

581624

PHB1
Prohibitin 1

1

2

Small-scale

0.479

High

581626

ZEB1
Zinc finger E-box-binding homeobox 1

1

4

High-throughput

0.479

High

581628

PBX1
Pre-B-cell leukemia transcription factor 1

1

3

Small-scale

0.479

High

581631

TAF6
Transcription initiation factor TFIID subunit 6

1

1

High-throughput

0.479

High

581634

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

14

High-throughput

0.479

High

581637

ZN121
Zinc finger protein 121

1

1

High-throughput

0.479

High

581641

CBX1
Chromobox protein homolog 1

1

4

Small-scale

0.479

High

581645

TLE1
Transducin-like enhancer protein 1

1

8

High-throughput

0.479

High

581646

TLE3
Transducin-like enhancer protein 3

1

8

High-throughput

0.479

High

581649

TLE5
TLE family member 5

1

6

High-throughput

0.479

High

581650

RBL2
Retinoblastoma-like protein 2

1

5

Small-scale

0.479

High

581653

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

581654

NFIA
Nuclear factor 1 A-type

1

6

High-throughput

0.479

High

581660

RBBP5
Retinoblastoma-binding protein 5

1

2

High-throughput

0.479

High

581661

SSXT
Protein SSXT

1

10

High-throughput

0.479

High

581662

EZH2
Histone-lysine N-methyltransferase EZH2

1

12

Small-scale

0.479

High

581665

ARI4B
AT-rich interactive domain-containing protein 4B

1

8

High-throughput

0.479

High

581666

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

1

High-throughput

0.479

High

581668

TAF3
Transcription initiation factor TFIID subunit 3

1

6

High-throughput

0.479

High

581669

NIPBL
Nipped-B-like protein

1

4

High-throughput

0.479

High

581670

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

581672

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

5

High-throughput

0.479

High

581676

BCOR
BCL-6 corepressor

1

10

High-throughput

0.479

High

581677

UBN2
Ubinuclein-2

1

8

High-throughput

0.479

High

581678

PAXI1
PAX-interacting protein 1

1

2

High-throughput

0.479

High

581680

TAD2B
Transcriptional adapter 2-beta

1

2

High-throughput

0.479

High

581683

PB1
Protein polybromo-1

1

10

High-throughput

0.479

High

581687

ARI3B
AT-rich interactive domain-containing protein 3B

1

6

High-throughput

0.479

High

581693

KMT2C
Histone-lysine N-methyltransferase 2C

1

16

High-throughput

0.479

High

581694

ARI1B
AT-rich interactive domain-containing protein 1B

1

8

High-throughput

0.479

High

581695

KDM2B
Lysine-specific demethylase 2B

1

4

High-throughput

0.479

High

581696

SMRC2
SWI/SNF complex subunit SMARCC2

1

10

High-throughput

0.479

High

581699

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

1

High-throughput

0.479

High

581701

ESR2
Estrogen receptor beta

1

8

Small-scale

0.479

High

581702

DPF1
Zinc finger protein neuro-d4

1

9

High-throughput

0.479

High

581703

REQU
Zinc finger protein ubi-d4

1

13

High-throughput

0.479

High

581705

KAT2A
Histone acetyltransferase KAT2A

1

20

High-throughput

0.479

High

581707

SMRC1
SWI/SNF complex subunit SMARCC1

1

5

High-throughput

0.479

High

581708

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

5

High-throughput

0.479

High

581710

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

7

High-throughput

0.479

High

581713

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.479

High

581715

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

4

High-throughput

0.479

High

581716

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

9

High-throughput

0.479

High

581717

EP400
E1A-binding protein p400

1

14

High-throughput

0.479

High

581718

ZN607
Zinc finger protein 607

1

1

High-throughput

0.479

High

581720

T22D3
TSC22 domain family protein 3

1

3

Small-scale

0.479

High

581723

ARI3A
AT-rich interactive domain-containing protein 3A

1

6

High-throughput

0.479

High

581729

ZN644
Zinc finger protein 644

1

3

High-throughput

0.479

High

581730

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

8

High-throughput

0.479

High

581734

TF7L2
Transcription factor 7-like 2

1

6

High-throughput

0.479

High

581735

MBIP1
MAP3K12-binding inhibitory protein 1

1

1

High-throughput

0.479

High

581737

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

1

High-throughput

0.479

High

581738

TRPS1
Zinc finger transcription factor Trps1

1

8

High-throughput

0.479

High

581740

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

581741

PRR12
Proline-rich protein 12

1

6

High-throughput

0.479

High

581742

TRI33
E3 ubiquitin-protein ligase TRIM33

1

9

High-throughput

0.479

High

581743

ZFP30
Zinc finger protein 30 homolog

1

2

High-throughput

0.479

High

581744

ZN281
Zinc finger protein 281

1

1

High-throughput

0.479

High

581745

SALL2
Sal-like protein 2

1

2

High-throughput

0.479

High

581746

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.479

High

581748

NCOR2
Nuclear receptor corepressor 2

1

8

High-throughput

0.479

High

581749

CABIN
Calcineurin-binding protein cabin-1

1

8

High-throughput

0.479

High

247647

NUPR1
Nuclear protein 1

1

0

Small-scale

0.458

High

581648

RING1
E3 ubiquitin-protein ligase RING1

1

0

High-throughput

0.458

High

581652

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.458

High

581657

SNW1
SNW domain-containing protein 1

1

0

Small-scale

0.458

High

581658

PEBB
Core-binding factor subunit beta

1

0

Small-scale

0.458

High

581663

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.458

High

581667

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.458

High

581682

PABP2
Polyadenylate-binding protein 2

1

0

Small-scale

0.458

High

581690

YAF2
YY1-associated factor 2

1

0

High-throughput

0.458

High

581691

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.458

High

581697

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.458

High

581700

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

581714

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

581725

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.458

High

581727

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

581731

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.458

High

581733

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.458

High

581736

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.458

High

581675

CASPC
Inactive caspase-12

1

1

High-throughput

0.457

High

581659

GSE1
Genetic suppressor element 1

1

1

High-throughput

0.437

High

581685

EX3L1
Exocyst complex component 3-like protein

2

0

High-throughput

0.316

High

581724

SMAKA
Small membrane A-kinase anchor protein

1

0

High-throughput

0.282

High

364117

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

0

Small-scale

0.275

Low

581621

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.249

Low

581664

GLO2
Hydroxyacylglutathione hydrolase, mitochondrial

1

0

High-throughput

0.249

Low

581671

MSD2
Myb/SANT-like DNA-binding domain-containing protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025