HitPredict

Interactor 1: GRM2 (Q14BI2)
Metabotropic glutamate receptor 2 (mGluR2)
Gene: GRM2

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030425 - dendrite GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0098978 - glutamatergic synapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 872 Mm			1 1186
+	Mm
		1112663 GRM3_MOUSE (1-872): 0: 844: 66.78		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112567 GRM5_MOUSE (13-833): 0: 778: 43.52		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		93828 E9QMC2_MOUSE (13-833): 0: 776: 43.52		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		956895 GRM1_MOUSE (11-833): 0: 744: 43.85		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Rn
		616094 GRM1_RAT (11-833): 0: 747: 43.97		AGAP2_RAT (1-1186): 0: 1019: 99.07