HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: MIA2 (Q96PC5)
Melanoma inhibitory activity protein 2 (MIA protein 2) (CTAGE family member 5 ER export factor) (Cutaneous T-cell lymphoma-associated antigen 5) (Meningioma-expressed antigen 6/11)
Gene: MIA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 1412
+	Hs
		1048158 TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59		EEA1_HUMAN (339-1297): 1.19e-41: 170: 8.91
+	Hs
		1047821 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		EEA1_HUMAN (339-1297): 1.19e-41: 170: 8.91
+	Hs
		556917 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		MYH7_HUMAN (766-1335): 1.48e-21: 104: 9.33
+	Hs
		563051 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		MYH8_HUMAN (787-1312): 2.29e-19: 97.2: 10.80
+	Hs
		535932 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		MYH3_HUMAN (906-1295): 1.23e-12: 75.2: 13.60
+	Hs
		556847 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		MYH1_HUMAN (917-1297): 1.16e-10: 68.7: 12.15
+	Hs
		1048147 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		MYH4_HUMAN (917-1297): 4.02e-10: 67.2: 12.15
+	Hs
		1048128 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		MYH2_HUMAN (986-1348): 3.28e-09: 64.1: 10.66