HitPredict

Interactor 1: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.751

Property	Details
Experiments	35271311, 26186194, 28514442, 33961781, 34761751, 19615732, 18922472, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 389 Hs			1 329
+	Hs
		121884 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Sp
		1013801 RPN7_SCHPO (9-387): 7.57e-96: 293: 42.78		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		1350850 RPN6_SCHPO (5-386): 3.53e-81: 256: 13.80		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		1062852 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		897284 CSN2_HUMAN (22-388): 5.37e-90: 280: 13.67		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		121825 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		888411 EIF3E_HUMAN (26-387): 7.71e-74: 238: 14.04		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29