Protein: RTC1
Restriction of telomere capping protein 1 (SEH-associated protein 2)

Gene: RTC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: Q08281

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0005774 - vacuolar membrane
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

916431

SEH1
Nucleoporin SEH1

4

20

Small-scale

0.878

High

794733

SEA4
SEH-associated protein 4

3

6

Small-scale

0.834

High

814937

NPR2
Nitrogen permease regulator 2

3

6

Small-scale

0.834

High

866250

IML1
Vacuolar membrane-associated protein IML1

3

13

Small-scale

0.834

High

1044264

WDR59
Maintenance of telomere capping protein 5

3

20

Small-scale

0.834

High

1046741

SEC13
Protein transport protein SEC13

2

20

Small-scale

0.767

High

834777

LST8
Target of rapamycin complex subunit LST8

1

17

High-throughput

0.646

High

803222

NPR3
Nitrogen permease regulator 3

3

1

Small-scale

0.646

High

444639

DED1
ATP-dependent RNA helicase DED1

1

9

High-throughput

0.578

High

584282

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

15

High-throughput

0.578

High

762874

TOR1
Serine/threonine-protein kinase TOR1

1

11

High-throughput

0.578

High

917496

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

5

High-throughput

0.578

High

948676

ACT
Actin

1

10

High-throughput

0.578

High

826410

MPH1
ATP-dependent DNA helicase MPH1

1

11

High-throughput

0.553

High

1062913

SUS1
SAGA complex subunit SUS1

1

1

High-throughput

0.541

High

510871

HSP77
Import motor subunit, mitochondrial

2

20

High-throughput

0.504

High

368764

PMG1
Phosphoglycerate mutase 1

1

2

High-throughput

0.500

High

420994

PMA1
Plasma membrane ATPase 1

1

2

High-throughput

0.500

High

572657

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.500

High

639081

VPS1
Vacuolar protein sorting-associated protein 1

1

6

High-throughput

0.500

High

647849

RFA1
Replication factor A protein 1

1

4

High-throughput

0.500

High

709481

HRR25
Casein kinase I homolog HRR25

1

14

High-throughput

0.500

High

1062906

BSC1
Bypass of stop codon protein 1

1

6

High-throughput

0.494

High

560771

KIN2
Serine/threonine-protein kinase KIN2

1

7

High-throughput

0.489

High

642487

MCK1
Protein kinase MCK1

1

9

High-throughput

0.489

High

394960

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.479

High

708387

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

734219

EF2
Elongation factor 2

1

9

High-throughput

0.479

High

748082

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

802808

OSH3
Oxysterol-binding protein homolog 3

1

3

High-throughput

0.479

High

1062912

YN034
Uncharacterized protein YNR034W-A

1

0

Small-scale

0.458

High

585394

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

6

High-throughput

0.457

High

692637

NSR1
Nuclear localization sequence-binding protein

1

5

High-throughput

0.457

High

806375

KOG1
Target of rapamycin complex 1 subunit KOG1

1

17

High-throughput

0.457

High

893243

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.457

High

1044486

RUVB1
RuvB-like protein 1

1

12

High-throughput

0.457

High

1050191

RRP5
rRNA biogenesis protein RRP5

1

9

High-throughput

0.457

High

1054259

FKBP4
FK506-binding protein 4

1

5

High-throughput

0.457

High

1062908

YRA1
RNA annealing protein YRA1

1

7

High-throughput

0.457

High

1062909

NOP56
Nucleolar protein 56

1

9

High-throughput

0.457

High

1062910

RUVB2
RuvB-like protein 2

1

12

High-throughput

0.457

High

1062911

NOP58
Nucleolar protein 58

1

9

High-throughput

0.457

High

393448

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.445

High

525374

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

527866

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

546546

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

671195

SIS1
Protein SIS1

1

10

High-throughput

0.445

High

742552

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

1056437

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

12

High-throughput

0.445

High

741158

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

4

High-throughput

0.437

High

748568

SC61A
Protein transport protein SEC61

1

2

High-throughput

0.437

High

798335

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.437

High

815259

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

4

High-throughput

0.437

High

816615

PXP1
2-hydroxyacyl-CoA lyase

1

4

High-throughput

0.437

High

1042254

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.437

High

1062907

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.437

High

653909

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

752823

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.407

High

805854

SPL2
Putative cyclin-dependent kinase inhibitor SPL2

1

0

High-throughput

0.282

High

1051993

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

High-throughput

0.282

High

1062905

SRL2
Protein SRL2

1

0

High-throughput

0.282

High

448477

RAD52
DNA repair and recombination protein RAD52

1

0

High-throughput

0.261

Low

736606

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.261

Low

744780

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.261

Low

798044

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025