HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29791485, 33618749
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 1292
+	Hs
		105900 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SPTN1_HUMAN (305-902): 3.99e-65: 246: 13.41
+	Hs
		105074 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SPTA1_HUMAN (317-1022): 7.88e-50: 196: 10.07
+	Hs
		105301 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PLCG1_HUMAN (394-880): 2.92e-43: 174: 11.75
+	Hs
		105927 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SRC8_HUMAN (1113-1288): 5.6e-22: 103: 19.21
+	Hs
		105993 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		ITSN1_HUMAN (492-1290): 3.41e-18: 93.3: 9.59
+	Hs
		104995 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SRBS2_HUMAN (63-924): 1.62e-11: 71.4: 12.11
+	Hs
		106187 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SH3R1_HUMAN (220-850): 9.48e-10: 65.2: 13.22