HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33618749
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 1100
+	Hs
		105074 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SPTA1_HUMAN (86-949): 9.2e-84: 301: 12.35
+	Hs
		105900 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34
+	Hs
		106308 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		KMT2C_HUMAN (153-1061): 1.14e-53: 208: 10.12
+	Hs
		105717 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		GRB2_HUMAN (743-922): 9e-28: 114: 17.99
+	Hs
		105993 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		ITSN1_HUMAN (131-934): 2.58e-19: 96.6: 10.20
+	Hs
		105927 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SRC8_HUMAN (918-1099): 5.82e-18: 90.8: 14.84
+	Hs
		106425 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SH3K1_HUMAN (942-1100): 2.46e-12: 73.2: 30.86
+	Hs
		106187 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SH3R1_HUMAN (981-1098): 4.67e-12: 72.6: 30.33
+	Hs
		106587 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		SRBS1_HUMAN (713-921): 7.57e-12: 72: 16.90
+	Hs
		106926 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		CD2AP_HUMAN (944-1100): 5.52e-12: 72: 29.70