HitPredict

Interactor 1: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Interactor 2: KDM1B (Q8NB78)
Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B)
Gene: KDM1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 726 Hs			1 822
+	Hs
		631509 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		KDM1B_HUMAN (1-822): 0: 1136: 100.00
+	Hs
		244669 BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56		KDM1B_HUMAN (1-822): 0: 1136: 100.00
+	Hs
		232586 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Mm
		1112509 Q3UH28_MOUSE (3-705): 1.82e-51: 195: 12.76		KDM1A_MOUSE (278-821): 2.04e-142: 443: 25.41
+	Hs
		232126 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Hs
		231897 BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Hs
		232000 TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41