HitPredict

Interactor 1: LGG1 (Q09490)
Protein lgg-1
Gene: lgg-1

Interactor 2: Q9N369 (Q9N369)
Ubiquitin-like-conjugating enzyme ATG3 (Autophagy-related protein 3)
Gene: atg-3

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26687600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0000407 - phagophore assembly site GO:0016236 - macroautophagy
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 123 Ce			1 305
+	At
		1082521 ATG8F_ARATH (2-116): 3.64e-62: 187: 56.52		ATG3_ARATH (4-305): 6.69e-126: 363: 39.37
+	Hs
		952359 GBRL2_HUMAN (1-116): 8.79e-59: 178: 57.76		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Hs
		328171 GBRAP_HUMAN (1-116): 1.57e-57: 175: 83.62		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Hs
		1430341 GBRL1_HUMAN (1-116): 5.6e-57: 173: 78.45		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Ce
		1171395 LGG2_CAEEL (4-116): 5.54e-41: 133: 31.30		Q9N369_CAEEL (1-305): 1.42e-132: 380: 100.00
+	Mm
		1362238 MLP3A_MOUSE (5-116): 3.27e-46: 146: 35.09		ATG3_MOUSE (1-305): 9.58e-127: 366: 50.16
+	Hs
		1417417 MLP3C_HUMAN (5-116): 5.25e-46: 147: 38.60		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Hs
		1433213 MLP3A_HUMAN (5-116): 3.27e-46: 146: 35.09		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Hs
		1428384 MLP3B_HUMAN (2-116): 9.88e-45: 143: 33.33		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Pf
		86837 Q8IJK2_PLAF7 (4-116): 3.36e-49: 154: 42.62		C0H519_PLAF7 (3-305): 1.5e-120: 350: 32.03
+	Hs
		64581 MP3B2_HUMAN (2-116): 7.65e-44: 141: 32.48		ATG3_HUMAN (1-305): 2.2e-125: 362: 49.53
+	Sc
		795384 ATG8_YEAST (1-116): 7.29e-60: 181: 53.45		ATG3_YEAST (8-302): 2.49e-100: 298: 34.26
+	Hs
		952339 GBRL2_HUMAN (1-116): 8.79e-59: 178: 57.76		ATG10_HUMAN (184-292): 3.32e-40: 141: 26.72
+	Hs
		328149 GBRAP_HUMAN (1-116): 1.57e-57: 175: 83.62		ATG10_HUMAN (184-292): 3.32e-40: 141: 26.72
+	Hs
		1430323 GBRL1_HUMAN (1-116): 5.6e-57: 173: 78.45		ATG10_HUMAN (184-292): 3.32e-40: 141: 26.72
+	Mm
		1341503 MLP3B_MOUSE (2-119): 7.71e-46: 146: 32.50		ATG10_MOUSE (162-292): 7.35e-41: 143: 23.91
+	Hs
		1417411 MLP3C_HUMAN (5-116): 5.25e-46: 147: 38.60		ATG10_HUMAN (184-292): 3.32e-40: 141: 26.72
+	Hs
		1428344 MLP3B_HUMAN (2-116): 9.88e-45: 143: 33.33		ATG10_HUMAN (184-292): 3.32e-40: 141: 26.72
+	Hs
		64579 MP3B2_HUMAN (2-116): 7.65e-44: 141: 32.48		ATG10_HUMAN (184-292): 3.32e-40: 141: 26.72