HitPredict

Interactor 1: MLP3C (Q9BXW4)
Microtubule-associated protein 1 light chain 3 gamma (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (Microtubule-associated proteins 1A/1B light chain 3C) (MAP1A/MAP1B LC3 C) (MAP1A/MAP1B light chain 3 C)
Gene: MAP1LC3C

Interactor 2: ATG3 (Q9NT62)
Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96)
Gene: ATG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 314
+	Hs
		328171 GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26		ATG3_HUMAN (1-314): 1.13e-158: 446: 100.00
+	Hs
		952359 GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98		ATG3_HUMAN (1-314): 1.13e-158: 446: 100.00
+	Mm
		1362238 MLP3A_MOUSE (7-126): 2.5e-53: 165: 59.17		ATG3_MOUSE (1-314): 2.93e-158: 446: 97.45
+	Hs
		1433213 MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17		ATG3_HUMAN (1-314): 1.13e-158: 446: 100.00
+	Hs
		1428384 MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55		ATG3_HUMAN (1-314): 1.13e-158: 446: 100.00
+	Hs
		1430341 GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47		ATG3_HUMAN (1-314): 1.13e-158: 446: 100.00
+	Hs
		64581 MP3B2_HUMAN (7-127): 1.02e-51: 162: 53.72		ATG3_HUMAN (1-314): 1.13e-158: 446: 100.00
+	At
		1082521 ATG8F_ARATH (9-126): 2.15e-58: 178: 42.37		ATG3_ARATH (17-314): 8.96e-122: 353: 46.41
+	Ce
		1067983 LGG1_CAEEL (12-126): 1.47e-52: 164: 38.26		Q9N369_CAEEL (1-314): 2.57e-119: 347: 49.22
+	Ce
		1171395 LGG2_CAEEL (10-126): 1.89e-44: 143: 47.01		Q9N369_CAEEL (1-314): 2.57e-119: 347: 49.22
+	Pf
		86837 Q8IJK2_PLAF7 (10-126): 2.31e-46: 148: 36.51		C0H519_PLAF7 (3-314): 9.85e-111: 325: 37.11
+	Sc
		795384 ATG8_YEAST (11-126): 1.29e-54: 169: 38.79		ATG3_YEAST (8-311): 1.53e-97: 291: 33.13
+	Hs
		1417411 MLP3C_HUMAN (1-147): 4.66e-72: 214: 100.00		ATG10_HUMAN (173-301): 3.28e-41: 144: 20.59
+	Mm
		1341503 MLP3B_MOUSE (7-126): 6.51e-53: 165: 55.00		ATG10_MOUSE (173-301): 3.92e-44: 151: 20.59
+	Hs
		328149 GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26		ATG10_HUMAN (173-301): 3.28e-41: 144: 20.59
+	Hs
		952339 GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98		ATG10_HUMAN (173-301): 3.28e-41: 144: 20.59
+	Hs
		1428344 MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55		ATG10_HUMAN (173-301): 3.28e-41: 144: 20.59
+	Hs
		1430323 GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47		ATG10_HUMAN (173-301): 3.28e-41: 144: 20.59
+	Hs
		64579 MP3B2_HUMAN (7-127): 1.02e-51: 162: 53.72		ATG10_HUMAN (173-301): 3.28e-41: 144: 20.59