HitPredict

Interactor 1: NH114 (G5EEM0)
Nuclear hormone receptor 114
Gene: nhr-114

Interactor 2: HIF1 (G5EGD2)
Hypoxia-inducible factor 1 (Hypoxia-induced factor 1)
Gene: hif-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Ce			1 719
+	Ce
		108094 NHR62_CAEEL (8-405): 5.57e-91: 285: 20.57		HIF1_CAEEL (1-719): 0: 731: 100.00
+	Hs
		126103 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		BMAL1_HUMAN (4-530): 3.58e-129: 398: 15.16
+	Hs
		369025 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		ARNT_HUMAN (2-560): 2.82e-131: 408: 18.03
+	Hs
		369703 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71
+	Hs
		370292 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		EPAS1_HUMAN (2-466): 7.27e-124: 391: 22.67
+	Hs
		587177 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78
+	Hs
		587173 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		NCOA2_HUMAN (2-576): 2.43e-98: 333: 15.71
+	Hs
		490101 COT1_HUMAN (2-413): 4.92e-100: 306: 18.93		NCOA2_HUMAN (2-576): 2.43e-98: 333: 15.71
+	Hs
		130328 NR5A2_HUMAN (9-410): 2.07e-97: 303: 18.32		NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78
+	Hs
		130327 NR5A2_HUMAN (9-410): 2.07e-97: 303: 18.32		NCOA2_HUMAN (2-576): 2.43e-98: 333: 15.71
+	Hs
		659718 RXRB_HUMAN (10-409): 9.25e-94: 293: 22.50		NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78
+	Hs
		369684 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78
+	Hs
		587195 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		NPAS2_HUMAN (1-533): 8.21e-95: 314: 15.21
+	Hs
		369673 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		NCOA2_HUMAN (2-576): 2.43e-98: 333: 15.71
+	Dm
		836362 HNF4_DROME (12-410): 5.03e-90: 288: 21.89		SIMA_DROME (3-642): 2.85e-96: 328: 21.40
+	Hs
		181498 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		CLOCK_HUMAN (4-535): 1.21e-91: 306: 16.13
+	Hs
		490089 COT1_HUMAN (2-413): 4.92e-100: 306: 18.93		AHR_HUMAN (4-456): 5.1e-92: 307: 16.07
+	Mm
		703484 STF1_MOUSE (9-411): 3.34e-91: 284: 19.83		NCOA1_MOUSE (2-586): 2.71e-93: 319: 13.92
+	Mm
		587102 ESR1_MOUSE (7-418): 2.5e-89: 284: 21.91		NCOA2_MOUSE (2-577): 3.9e-92: 316: 15.36
+	Hs
		369099 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		AHR_HUMAN (4-456): 5.1e-92: 307: 16.07