HitPredict

Interactor 1: HIF1 (G5EGD2)
Hypoxia-inducible factor 1 (Hypoxia-induced factor 1)
Gene: hif-1

Interactor 2: Q18477 (Q18477)
Histone deacetylase domain-containing protein
Gene: hda-11

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 719 Ce			1 334
+	Hs
		649101 ARNT_HUMAN (2-560): 2.82e-131: 408: 18.03		HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59
+	Hs
		1038422 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59
+	Hs
		1038669 EPAS1_HUMAN (2-466): 7.27e-124: 391: 22.67		HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59
+	Hs
		1085622 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76
+	Hs
		177311 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		HDAC3_HUMAN (17-314): 2.9e-118: 349: 21.47
+	Hs
		1270407 EPAS1_HUMAN (2-466): 7.27e-124: 391: 22.67		HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76
+	Hs
		1085703 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		HDAC6_HUMAN (19-327): 2.83e-97: 313: 20.96
+	Hs
		177366 NPAS1_HUMAN (11-521): 8.05e-101: 323: 17.64		HDAC3_HUMAN (17-314): 2.9e-118: 349: 21.47