Protein: TRPS1
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)

Gene: TRPS1
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q9UHF7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001501 - skeletal system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317027

MTA2
Metastasis-associated protein MTA2

2

20

High-throughput

0.776

High

1102681

MTA1
Metastasis-associated protein MTA1

2

20

High-throughput

0.776

High

1295322

P66A
Transcriptional repressor p66-alpha

2

10

High-throughput

0.776

High

1361032

P66B
Transcriptional repressor p66-beta

2

10

High-throughput

0.776

High

1413360

MTA3
Metastasis-associated protein MTA3

2

20

High-throughput

0.776

High

1103430

CTBP1
C-terminal-binding protein 1

6

9

High-throughput

0.732

High

991756

DYL1
Dynein light chain 1, cytoplasmic

4

2

Small-scale

0.709

High

1110155

HDAC1
Histone deacetylase 1

4

20

High-throughput

0.691

High

1368186

HDAC2
Histone deacetylase 2

4

20

Small-scale

0.691

High

1066536

RBBP4
Histone-binding protein RBBP4

3

13

High-throughput

0.662

High

993797

UBC9
SUMO-conjugating enzyme UBC9

2

8

Small-scale

0.636

High

397159

ESR1
Estrogen receptor

3

20

High-throughput

0.633

High

1093076

CDC16
Cell division cycle protein 16 homolog

2

5

High-throughput

0.628

High

1458345

NLK
Serine/threonine-protein kinase NLK

2

7

High-throughput

0.628

High

662513

GATA2
Endothelial transcription factor GATA-2

1

15

High-throughput

0.618

High

662668

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

15

High-throughput

0.618

High

877573

LHX1
LIM/homeobox protein Lhx1

1

17

High-throughput

0.618

High

895812

LHX2
LIM/homeobox protein Lhx2

1

20

High-throughput

0.618

High

1379963

LHX4
LIM/homeobox protein Lhx4

1

20

High-throughput

0.618

High

1458641

LHX3
LIM/homeobox protein Lhx3

1

20

High-throughput

0.618

High

1390744

DYL2
Dynein light chain 2, cytoplasmic

2

2

High-throughput

0.611

High

1458456

UXT
Protein UXT

2

0

High-throughput

0.602

High

352262

MBD3
Methyl-CpG-binding domain protein 3

2

9

High-throughput

0.601

High

1088080

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.601

High

1088604

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

20

High-throughput

0.601

High

1099807

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

3

High-throughput

0.601

High

1133032

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

20

High-throughput

0.601

High

1458212

MBD2
Methyl-CpG-binding domain protein 2

2

9

High-throughput

0.601

High

143310

NFIB
Nuclear factor 1 B-type

2

19

High-throughput

0.584

High

474352

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

872848

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

1133718

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

943871

CF298
Cilia- and flagella-associated protein 298

1

1

High-throughput

0.541

High

155368

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

3

High-throughput

0.536

High

340947

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

10

High-throughput

0.536

High

549355

SRF
Serum response factor

1

4

High-throughput

0.536

High

691871

MK03
Mitogen-activated protein kinase 3

1

4

High-throughput

0.536

High

703736

MK01
Mitogen-activated protein kinase 1

1

4

High-throughput

0.536

High

941592

CTBP2
C-terminal-binding protein 2

1

9

High-throughput

0.536

High

1057665

CDK18
Cyclin-dependent kinase 18

1

6

High-throughput

0.536

High

1128307

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.536

High

1150268

TEAD2
Transcriptional enhancer factor TEF-4

1

1

High-throughput

0.536

High

1155996

ZFHX3
Zinc finger homeobox protein 3

1

8

High-throughput

0.536

High

1213157

BEND3
BEN domain-containing protein 3

1

3

High-throughput

0.536

High

1453807

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

1005222

RNF4
E3 ubiquitin-protein ligase RNF4

1

11

Small-scale

0.534

High

175251

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.489

High

1023985

EM55
55 kDa erythrocyte membrane protein

1

1

High-throughput

0.489

High

1453644

PALS2
Protein PALS2

1

1

High-throughput

0.489

High

991454

SUMO1
Small ubiquitin-related modifier 1

1

4

Small-scale

0.481

High

124661

EYA2
Protein phosphatase EYA2

1

11

High-throughput

0.479

High

129524

MEN1
Menin

1

1

High-throughput

0.479

High

181575

TBXT
T-box transcription factor T

1

6

High-throughput

0.479

High

210140

CRX
Cone-rod homeobox protein

1

14

High-throughput

0.479

High

225135

TLX3
T-cell leukemia homeobox protein 3

1

18

High-throughput

0.479

High

240010

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

247015

KDM1A
Lysine-specific histone demethylase 1A

1

16

High-throughput

0.479

High

260580

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

289187

PRDM1
PR domain zinc finger protein 1

1

5

High-throughput

0.479

High

299494

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

3

Small-scale

0.479

High

339883

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

404525

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

519432

MYB
Transcriptional activator Myb

1

4

High-throughput

0.479

High

520431

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

538485

EGR2
E3 SUMO-protein ligase EGR2

1

2

High-throughput

0.479

High

540965

ERG
Transcriptional regulator ERG

1

10

High-throughput

0.479

High

577508

ETS1
Protein C-ets-1

1

10

High-throughput

0.479

High

581738

MYOD1
Myoblast determination protein 1

1

8

High-throughput

0.479

High

589970

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

659313

SP100
Nuclear autoantigen Sp-100

1

17

High-throughput

0.479

High

662292

PAX7
Paired box protein Pax-7

1

17

High-throughput

0.479

High

685376

PAX6
Paired box protein Pax-6

1

12

High-throughput

0.479

High

696792

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

703212

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

725333

TLX1
T-cell leukemia homeobox protein 1

1

15

High-throughput

0.479

High

769444

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

775926

HNF1B
Hepatocyte nuclear factor 1-beta

1

11

High-throughput

0.479

High

776146

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776263

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

789589

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

High-throughput

0.479

High

834083

HNF4A
Hepatocyte nuclear factor 4-alpha

1

15

High-throughput

0.479

High

837102

ELK3
ETS domain-containing protein Elk-3

1

10

High-throughput

0.479

High

873128

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

937957

FOXA1
Hepatocyte nuclear factor 3-alpha

1

20

High-throughput

0.479

High

938516

PAX9
Paired box protein Pax-9

1

10

High-throughput

0.479

High

942127

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.479

High

942475

GSC
Homeobox protein goosecoid

1

17

High-throughput

0.479

High

944758

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

1037907

HEN1
Helix-loop-helix protein 1

1

9

High-throughput

0.479

High

1040088

PAX2
Paired box protein Pax-2

1

11

High-throughput

0.479

High

1040930

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.479

High

1045877

TF65
Transcription factor p65

1

9

High-throughput

0.479

High

1048122

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

1052919

HME1
Homeobox protein engrailed-1

1

13

High-throughput

0.479

High

1056660

PAX8
Paired box protein Pax-8

1

13

High-throughput

0.479

High

1089048

TP53B
TP53-binding protein 1

1

2

High-throughput

0.479

High

1091261

FOXI1
Forkhead box protein I1

1

19

High-throughput

0.479

High

1091367

FOXL1
Forkhead box protein L1

1

17

High-throughput

0.479

High

1094650

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

3

Small-scale

0.479

High

1114576

CUL3
Cullin-3

1

18

High-throughput

0.479

High

1118790

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

1160901

TBR1
T-box brain protein 1

1

6

High-throughput

0.479

High

1247035

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1351188

SP7
Transcription factor Sp7

1

14

High-throughput

0.479

High

1359719

PHIP
PH-interacting protein

1

17

High-throughput

0.479

High

1384466

PF21A
PHD finger protein 21A

1

18

High-throughput

0.479

High

1401431

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1405450

FEV
Protein FEV

1

10

High-throughput

0.479

High

1413238

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1416940

KLF16
Krueppel-like factor 16

1

18

High-throughput

0.479

High

1420516

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.479

High

1434982

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1453588

VSX1
Visual system homeobox 1

1

11

High-throughput

0.479

High

1458814

ZMYM2
Zinc finger MYM-type protein 2

1

2

High-throughput

0.479

High

1459931

XPO7
Exportin-7

1

5

High-throughput

0.479

High

1459932

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1459933

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

1459935

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

194385

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

337406

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

378524

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

1214597

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1276923

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1364002

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1415901

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1459934

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

765976

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.445

High

1351293

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

20

High-throughput

0.445

High

1453273

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

106803

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1135156

CUL7
Cullin-7

1

2

High-throughput

0.437

High

1290371

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.426

High

1328691

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

High-throughput

0.407

High

1278588

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

3

0

High-throughput

0.345

High

1390364

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1143298

PLEC
Plectin

1

0

High-throughput

0.269

Low

530976

CO7
Complement component C7

1

0

High-throughput

0.232

Low

1396588

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025