HitPredict

Interactor 1: PKN1 (Q16512)
Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)
Gene: PKN1

Interactor 2: PKN1 (Q16512)
Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)
Gene: PKN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.735

The method score is based on:

Property Details
Experiments 14741690
Identification Methods enzymatic study, in-gel kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0001782 - B cell homeostasis
GO:0001783 - B cell apoptotic process
GO:0001933 - negative regulation of protein phosphorylation
GO:0002634 - regulation of germinal center formation
GO:0002637 - regulation of immunoglobulin production
and 33 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 942
Hs

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Last updated: 15 Jul 2024