HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: MB3L1 (Q8WWY6)
Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)
Gene: MBD3L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 15456747, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 194
+	Hs
		328566 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Hs
		1083414 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Hs
		1083320 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73
+	Hs
		328538 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Hs
		997830 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		MB3L1_HUMAN (1-194): 1.26e-98: 285: 100.00
+	Hs
		997938 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Dm
		1099165 CAF1_DROME (1-209): 8.04e-42: 154: 13.16		Q9VHB7_DROME (19-172): 3.67e-59: 190: 28.66
+	Hs
		997820 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73