Interactor 1: NOP2 (P40991)
25S rRNA (cytosine(2870)-C(5))-methyltransferase (EC 2.1.1.310) (Nucleolar protein 2)
Gene: NOP2

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 11805826, 30568249, 31511893, 16429126, 34686661, 37968396, 37811893
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0030687 - preribosome, large subunit precursor
GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 618
Sc

1 505
+ Sc
+ Sc
+ Dm
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Dm
+ Dm
+ Sc
+ Sc

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Last updated: 15 Jul 2024