HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: Q32MK9 (Q32MK9)
HCG2039195, isoform CRA_a (ZNF509 protein)
Gene: ZNF509

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Hs			1 248
+	Hs
		585025 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZN250_HUMAN (3-127): 5.23e-51: 176: 27.78
+	Hs
		1090735 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZBT49_HUMAN (18-152): 2.04e-30: 120: 23.94
+	Hs
		1090720 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZN544_HUMAN (87-247): 2.79e-22: 97: 6.07
+	Hs
		567173 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZNF35_HUMAN (177-246): 3.23e-22: 96.6: 14.29
+	Hs
		1090884 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZKSC3_HUMAN (29-185): 3.51e-22: 96.5: 19.43
+	Hs
		1090734 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZN662_HUMAN (2-64): 1.45e-21: 94.2: 39.68
+	Hs
		1090747 TRAF2_HUMAN (1-501): 1.2e-158: 461: 100.00		ZN572_HUMAN (15-68): 1.84e-11: 65.5: 55.56
+	Hs
		1094916 TRAF3_HUMAN (16-501): 1.77e-110: 340: 31.42		ZBT49_HUMAN (18-152): 2.04e-30: 120: 23.94
+	Hs
		585026 TRAF1_HUMAN (130-499): 4.41e-88: 278: 37.44		ZN250_HUMAN (3-127): 5.23e-51: 176: 27.78
+	Hs
		600514 TRAF4_HUMAN (17-498): 2.23e-93: 293: 29.12		ZNF3_HUMAN (121-247): 9.12e-45: 157: 11.24
+	Hs
		1287944 TRAF4_HUMAN (17-498): 2.23e-93: 293: 29.12		Q86U76_HUMAN (121-247): 2.71e-43: 152: 11.24
+	Hs
		1093856 TRAF1_HUMAN (130-499): 4.41e-88: 278: 37.44		ZN662_HUMAN (2-64): 1.45e-21: 94.2: 39.68
+	Hs
		1093862 TRAF1_HUMAN (130-499): 4.41e-88: 278: 37.44		ZN572_HUMAN (15-68): 1.84e-11: 65.5: 55.56
+	Hs
		585112 TRIM1_HUMAN (7-374): 3.67e-42: 162: 16.15		ZN250_HUMAN (3-127): 5.23e-51: 176: 27.78
+	Hs
		623399 RO52_HUMAN (28-368): 5.33e-58: 201: 12.68		ZBT49_HUMAN (18-152): 2.04e-30: 120: 23.94
+	Hs
		1066108 TRI39_HUMAN (26-347): 1.87e-42: 160: 11.91		ZN543_HUMAN (2-113): 1.36e-40: 148: 39.82
+	Hs
		600073 TRI39_HUMAN (26-347): 1.87e-42: 160: 11.91		ZNF19_HUMAN (162-247): 5.91e-22: 95.4: 9.68
+	Hs
		601982 TRI39_HUMAN (26-347): 1.87e-42: 160: 11.91		ZNF8_HUMAN (43-152): 2.17e-21: 94.6: 22.22
+	Hs
		1277133 TRIM1_HUMAN (7-374): 3.67e-42: 162: 16.15		ZN572_HUMAN (15-68): 1.84e-11: 65.5: 55.56
+	Hs
		67049 TRI39_HUMAN (26-347): 1.87e-42: 160: 11.91		ZN726_HUMAN (7-89): 3.79e-09: 58.5: 39.76