HitPredict

Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: HECW2 (Q9P2P5)
E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2)
Gene: HECW2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24163370
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0072686 - mitotic spindle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 1572
+	Hs
		718643 CDC27_HUMAN (4-197): 7.27e-15: 80.2: 16.50		HECW2_HUMAN (1-1572): 0: 1322: 100.00
+	Hs
		1243874 CTR9_HUMAN (3-278): 1.14e-09: 63.6: 9.03		HECW2_HUMAN (1-1572): 0: 1322: 100.00
+	Hs
		1454767 CDC23_HUMAN (9-282): 1.24e-09: 63.3: 10.55		HECW2_HUMAN (1-1572): 0: 1322: 100.00
+	Hs
		185816 OGT1_HUMAN (3-449): 8.08e-56: 206: 10.82		HUWE1_HUMAN (1007-1571): 6.06e-165: 557: 30.48
+	Mm
		1274322 OGT1_MOUSE (3-449): 7.35e-56: 206: 11.04		HUWE1_MOUSE (1002-1571): 8.01e-152: 518: 31.45
+	Hs
		1280583 APC7_HUMAN (67-612): 8.03e-23: 104: 11.25		HUWE1_HUMAN (1007-1571): 6.06e-165: 557: 30.48
+	Hs
		1280582 CDC23_HUMAN (9-282): 1.24e-09: 63.3: 10.55		HUWE1_HUMAN (1007-1571): 6.06e-165: 557: 30.48
+	Hs
		131583 OGT1_HUMAN (3-449): 8.08e-56: 206: 10.82		WWP2_HUMAN (665-1078): 1.98e-14: 80.8: 16.39
+	Hs
		186040 OGT1_HUMAN (3-449): 8.08e-56: 206: 10.82		SMUF1_HUMAN (680-902): 1.41e-12: 74.7: 15.19